Association of Serum Dupilumab Levels at 16 Weeks With Treatment Response and Adverse Effects in Patients With Atopic Dermatitis: A Prospective Clinical Cohort Study From the BioDay Registry.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4639
Abstract: Importance The registered dose of dupilumab for adult patients with atopic dermatitis (AD) is 300 mg every other week. At present, it is unknown whether serum dupilumab levels are associated with treatment response or adverse… read more here.
Keywords: adverse effects; serum dupilumab; treatment response; dupilumab levels ... See more keywords
Expectations and Prior Experiences Associated With Adverse Effects of COVID-19 Vaccination
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.4732
Abstract: Key Points Question Are positive and negative expectations prior to COVID-19 vaccination associated with systemic adverse effects in individuals receiving their second dose of COVID-19 vaccines? Findings In this cohort study of 1678 participants, expectations… read more here.
Keywords: expectations prior; vaccination; adverse effects; covid vaccination ... See more keywords
Prediction Tools for Psychiatric Adverse Effects After Levetiracetam Prescription
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2018.4561
Abstract: Importance Levetiracetam is a commonly used antiepileptic drug, yet psychiatric adverse effects are common and may lead to treatment discontinuation. Objective To derive prediction models to estimate the risk of psychiatric adverse effects from levetiracetam… read more here.
Keywords: psychiatric adverse; prescription; adverse effects; effects levetiracetam ... See more keywords
Misinterpretation of Surgeons' Statements on Cancer Removal-The Adverse Effects of "We Got It All".
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.3769
Abstract: This Viewpoint describes the miscommunication and potential adverse effects of the phrase “we got it all” after cancer surgery and advises using with caution. read more here.
Keywords: statements cancer; adverse effects; cancer removal; misinterpretation surgeons ... See more keywords
Association of Serious Adverse Effects With the Contamination of Ocular Medications-A Global Perspective.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.1549
Abstract: This Viewpoint offers examples of the causes of infectious keratitis around the world and emphasizes the need for vigilance among ophthalmologists to reduce the risk of sight-threatening complications. read more here.
Keywords: association serious; adverse effects; contamination ocular; serious adverse ... See more keywords
Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.31961
Abstract: I read with interest the recent report by Maraka et al, which described the results of a phase 1 study of temozolomide together with combinations of repurposed memantine, metformin, and mefloquine for the treatment of… read more here.
Keywords: treatment; study; drug; neuropsychiatric adverse ... See more keywords
Naringin treatment improved main clozapine-induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21800
Abstract: Schizophrenia is one of the major neuropsychiatric disorders affecting people worldwide. Unfortunately, currently available antipsychotic medications possess several side effects. Among them, clozapine is one of the atypical antipsychotics prescribed in schizophrenia wing to its… read more here.
Keywords: clozapine; treatment; adverse effects; naringin treatment ... See more keywords
Research Advances on the Adverse Effects of Nanomaterials in a Model Organism Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.5133
Abstract: Along with the rapid development of nanotechnology, the bio-safety assessment of nanotechnology products, including nanomaterials, becomes more and more important. Nematode Caenorhabditis elegans (C. elegans) is a valuable model organism that has been widely used… read more here.
Keywords: model organism; caenorhabditis elegans; effects nanomaterials; nanotechnology ... See more keywords
Adverse effects of vaccination against sars-cov2 in patients with preexisting chronic liver disease: A real-world study
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DOI: 10.1002/hep.32188
Abstract: Background: Information about effects of vaccination against SARS-CoV2 in patients with preexisting chronic liver disease is insufficient. The present study aims to describe the prevalence of adverse effects associated with vaccination against SARS-CoV2 in patients… read more here.
Keywords: chronic liver; sars cov2; liver disease; liver ... See more keywords
Propylparaben concentrations in the urine of women and adverse effects on ovarian function in mice in vivo and ovarian cells in vitro
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4225
Abstract: Female reproduction is precisely regulated by hormones, and the ovary is easily affected by environmental endocrine disruptors (EDCs), which are ubiquitous in industrialized societies. Parabens are EDCs that are used as antibacterial preservatives in cosmetics,… read more here.
Keywords: effects ovarian; adverse effects; concentrations urine; mice ... See more keywords
Targeting Bortezomib to Bone Increases Its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3889
Abstract: Bortezomib (Btz) is a proteasome inhibitor approved by the FDA to treat multiple myeloma. It also increases bone volume by promoting osteoblast differentiation and inhibiting osteoclastogenesis in mice. However, Btz has severe systemic adverse effects,… read more here.
Keywords: systemic adverse; bone anabolic; bone; mice ... See more keywords