Independent validation of a pre-specified four-kallikrein marker model for prediction of adverse pathology and biochemical recurrence.
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DOI: 10.1038/s41416-021-01661-x
Abstract: BACKGROUND Accurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has an undefined role in predicting outcomes after radical prostatectomy (RP). METHODS We included 1476 patients with… read more here.
Keywords: pathology biochemical; prediction adverse; adverse pathology; model ... See more keywords
Re: A 17-Gene Panel for Prediction of Adverse Prostate Cancer Pathologic Features: Prospective Clinical Validation and Utility.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Urology"
DOI: 10.1097/01.ju.0000559603.17907.5a
Abstract: available at http://www.ncbi.nlm.nih.gov/pubmed/30611659 Editorial Comment: In this prospective evaluation of the Oncotype DX genomic test 1,200 men with very low, low or favorable intermediate risk prostate cancer were enrolled in a multicenter evaluation of the… read more here.
Keywords: pathology; adverse pathology; prostate cancer; risk ... See more keywords
A 17-Gene Genomic Prostate Score as a Predictor of Adverse Pathology for Men on Active Surveillance.
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DOI: 10.1097/ju.0000000000000290
Abstract: INTRODUCTION AND OBJECTIVE OncotypeDx Genomic Prostate Score (GPS) test is an RNA expression assay that can be performed on prostate biopsies. We sought to determine whether GPS was associated with increased risk of adverse pathology… read more here.
Keywords: prostate; pathology; risk; adverse pathology ... See more keywords
Influence of common comorbid conditions on a 17-gene assay for prediction of adverse pathology in clinically low-risk prostate cancer.
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DOI: 10.1200/jco.2017.35.6_suppl.91
Abstract: 91Background: Well-validated molecular biomarkers can improve risk stratification in newly diagnosed PCa. It is important to demonstrate that biomarkers are not influenced by common clinical conditions. A 17-gene biopsy-based RT-PCR assay (Oncotype Genomic Prostate Score,… read more here.
Keywords: risk; adverse pathology; pathology; comorbid conditions ... See more keywords
Adverse pathology as a predictor of distant metastasis and prostate cancer mortality with 20-year follow up.
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DOI: 10.1200/jco.2021.39.6_suppl.219
Abstract: 219Background: Adverse pathology (AP) at radical prostatectomy (RP) is often used as a proxy for long-term prostate cancer outcomes. The goal of this study was to assess the association of AP at RP... read more here.
Keywords: pathology; prostate cancer; pathology predictor; adverse pathology ... See more keywords