Abstract Tu0067: A Genome-wide CRISPRi Screen Implicates Coronary Artery Disease GWAS Genes as Key Regulators of Adventitial Fibroblast Proliferation
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DOI: 10.1161/atv.45.suppl_1.tu0067
Abstract: Background: Vascular diseases, including atherosclerosis and aneurysms, are the leading causes of death in the US and world-wide. Spatial transcriptomics alongside lineage-tracing and lineage-ablation data implicates critical roles for adventitial fibroblasts (AdvFibs) in both atherosclerosis… read more here.
Keywords: advfib activation; crispri screen; genome wide; activation ... See more keywords