Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodeling.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular research"
DOI: 10.1093/cvr/cvab174
Abstract: Cardiovascular diseases are characterized by chronic vascular dysfunction and provoke pathological remodeling events such as neointima formation, atherosclerotic lesion development, and adventitial fibrosis. While lineage-tracing studies have shown that phenotypically modulated smooth muscle cells (SMCs)… read more here.
Keywords: progenitor cells; vascular homeostasis; vascular remodeling; adventitial progenitor ... See more keywords
Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4
Sign Up to like & getrecommendations! Published in 2017 at "Circulation Research"
DOI: 10.1161/circresaha.116.309322
Abstract: Rationale: The vascular adventitia is a complex layer of the vessel wall consisting of vasa vasorum microvessels, nerves, fibroblasts, immune cells, and resident progenitor cells. Adventitial progenitors express the stem cell markers, Sca1 and CD34… read more here.
Keywords: progenitor cells; subpopulation; advsca1 cells; smooth muscle ... See more keywords