The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity
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DOI: 10.1016/j.neuropharm.2016.11.016
Abstract: ABSTRACT Positive allosteric modulation of the GABAB receptor is a promising alternative to direct activation of the receptor as a therapeutic approach for treatment of addiction, chronic pain, anxiety, epilepsy, autism, Fragile X syndrome, and… read more here.
Keywords: novel potent; adx71441; positive allosteric; gabab receptor ... See more keywords