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   Articles with "aep" as a keyword



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UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202103396

Abstract: Netrin‐1 is a chemotropic cue mediating axon growth and neural migration in neuronal development, and its receptors deletion in colorectal cancer and UNC5s act as dependence receptors regulating neuronal apoptosis. Asparagine endopeptidase (AEP) is an… read more here.

Keywords: unc5c receptor; aep; dopaminergic neuronal; parkinson disease ... See more keywords

The exosomal integrin α5β1/AEP complex derived from epithelial ovarian cancer cells promotes peritoneal metastasis through regulating mesothelial cell proliferation and migration

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recommendations! Published in 2020 at "Cellular Oncology"

DOI: 10.1007/s13402-019-00486-4

Abstract: Purpose Epithelial ovarian cancer (EOC) is one of the most malignant cancers in the gynecologic system. Many patients are diagnosed at an advanced stage with disseminated intra-peritoneal metastases. EOC spreads via both direct extension and… read more here.

Keywords: itga5b1 aep; epithelial ovarian; aep; aep complex ... See more keywords
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Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause

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recommendations! Published in 2017 at "Chest"

DOI: 10.1016/j.chest.2017.03.001

Abstract: Background Acute eosinophilic pneumonia (AEP) is an uncommon disease, often indistinguishable from ARDS or community‐acquired pneumonia at initial presentation. AEP can be idiopathic, but identifiable causes include medications and inhalational exposures, including cigarette smoke. Methods… read more here.

Keywords: aep; acute eosinophilic; medication related; eosinophilic pneumonia ... See more keywords
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Drug reservoir mechanism of Pt(II)-sulfur chelates based on pharmacokinetics of Pt(II) complex with thiols & thio-ethers: An experimental and theoretical approach

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recommendations! Published in 2020 at "Inorganica Chimica Acta"

DOI: 10.1016/j.ica.2020.120202

Abstract: Abstract Dichloro Pt(II) complex, Cis-[Pt(AEP)Cl2], C-1 was synthesized with bidentate chelating ligand 1-(2-Aminoethyl)-pyrrolidine (AEP) and hydrolyzed to the corresponding complex [Pt(AEP)(OH2)2](ClO4)2, C-2 to investigate their pharmacokinetics and theoretical study. Bio-relevant tri-peptide glutathione (GSH) and amino… read more here.

Keywords: aep; sulfur; drug reservoir; mechanism ... See more keywords
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PD‐1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

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recommendations! Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2018.05.006

Abstract: SUMMARY CD4+ T cell differentiation into multiple T helper (Th) cell lineages is critical for optimal adaptive immune responses. This report identifies an intrinsic mechanism by which programmed death‐1 receptor (PD‐1) signaling imparted regulatory phenotype… read more here.

Keywords: th1 cells; aep; asparaginyl endopeptidase; itreg cells ... See more keywords
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Synthesis of an effective bio-based flame-retardant curing agent and its application in epoxy resin: Curing behavior, thermal stability and flame retardancy

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recommendations! Published in 2019 at "Polymer Degradation and Stability"

DOI: 10.1016/j.polymdegradstab.2019.07.005

Abstract: Abstract In this work, a bio-based macromolecule ammonium phytic acid named as PA-AEP was synthesized successfully via neutralization reaction between phytic acid (PA) and N-aminoethylpiperazine (AEP) and served as a monocomponent flame-retardant curing agent to… read more here.

Keywords: epoxy resin; flame; flame retardancy; aep ... See more keywords
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Effect of aquatic exercise programs according to the International Classification of Functionality, Disability and Health domains in individuals with Parkinson's disease: a systematic review and meta-analysis with GRADE quality assessment.

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recommendations! Published in 2023 at "Disability and rehabilitation"

DOI: 10.1080/09638288.2022.2164800

Abstract: PURPOSE To investigate the effects of aquatic exercise programs (AEP) in body structure and function, activity, and participation outcomes in individuals with Parkinson's disease (PD) with mild to moderate disability levels. METHODS Six databases were… read more here.

Keywords: structure function; disability; aep; body structure ... See more keywords
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Role of asparagine endopeptidase in mediating wild-type p53 inactivation of glioblastoma.

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recommendations! Published in 2019 at "Journal of the National Cancer Institute"

DOI: 10.1093/jnci/djz155

Abstract: BACKGROUND Isocitrate dehydrogenase (IDH)-wild-type (WT) glioblastoma (GBM) accounts for 90% of all GBMs, while only 27% of IDH-WT-GBMs have p53 mutations. However, the tumor surveillance function of WT-p53 in GBM is subverted by mechanisms that… read more here.

Keywords: glioblastoma; aep; inactivation; p53 ... See more keywords
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Acute Eosinophilic Pneumonia. Causes, Diagnosis, and Management

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recommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"

DOI: 10.1164/rccm.201710-1967ci

Abstract: &NA; Acute eosinophilic pneumonia (AEP) is an uncommon acute respiratory illness of varying severity that includes presentation as acute respiratory distress syndrome with fatal outcome. AEP may be idiopathic, but identifiable causes include smoking and… read more here.

Keywords: eosinophilic pneumonia; aep; management; acute eosinophilic ... See more keywords

Foaming epoxy-amine-carbamate: The effect of different neat amines on rheological and cellular morphology

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recommendations! Published in 2023 at "Journal of Cellular Plastics"

DOI: 10.1177/0021955x231166007

Abstract: The use of carbamate to foam epoxy depends significantly on the precured modulus to stabilize the cellular structure. The optimum precured modulus is developed from the reaction of epoxy resin and the neat amine. The… read more here.

Keywords: aep; effect; amine; carbamate ... See more keywords
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First-Line Chemo-Immunotherapy for Extensive-Stage Small-Cell Lung Cancer: A United States-Based Cost-Effectiveness Analysis

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recommendations! Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.699781

Abstract: Objective This study aimed to assess the cost-effectiveness of two recently approved first-line chemo-immunotherapies [atezolizumab combined with etoposide and platinum (AEP) and durvalumab combined with etoposide and platinum (DEP)] for patients with extensive-stage small-cell lung… read more here.

Keywords: first line; cost effectiveness; aep; cost ... See more keywords