Nano-in-Microparticles for Aerosol Delivery of Antibiotic-loaded, Fucose-derivatized and Macrophage-targeted Liposomes to Combat Mycobacterial Infections: In Vitro deposition, Pulmonary Barrier Interactions and Targeted Delivery.
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DOI: 10.1002/adhm.202102117
Abstract: XXXX This article is protected by copyright. All rights reserved. read more here.
Keywords: delivery antibiotic; delivery; antibiotic loaded; aerosol delivery ... See more keywords
Efficient Nose-to-Lung Aerosol Delivery with an Inline DPI Requiring Low Actuation Air Volume
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DOI: 10.1007/s11095-018-2473-7
Abstract: PurposeTo demonstrate efficient aerosol delivery through an in vitro nasal model using a dry powder inhaler (DPI) requiring low actuation air volumes (LV) applied during low-flow nasal cannula (LFNC) therapy.MethodsA previously developed LV-DPI was connected… read more here.
Keywords: aerosol delivery; system; delivery; dpi requiring ... See more keywords
Development of an Infant Air-Jet Dry Powder Aerosol Delivery System (iDP-ADS) Including a New Multifunctional Bifurcating Two-Prong Nasal Interface
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DOI: 10.1007/s11095-024-03814-y
Abstract: To improve the quality of aerosol delivery to infants, the iDP-ADS was advanced to include dual-prong nose-to-lung aerosol administration with a bifurcating interface, consistently monitor lung pressures and control ventilatory parameters with a pressure monitoring… read more here.
Keywords: idp ads; full term; delivery; aerosol delivery ... See more keywords
Nebulizers and spacers for aerosol delivery through adult nasal cannula at low oxygen flow rate: An in-vitro study
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DOI: 10.1016/j.jddst.2017.04.014
Abstract: Abstract Combining oxygen therapy with aerosol delivery within High flow nasal cannula oxygen therapy (HFNC) is an attractive practice. Delivered dose (DD) was found to decrease with increasing gas flow rates and with smaller sized… read more here.
Keywords: oxygen; aerosol delivery; low oxygen; oxygen flow ... See more keywords
Update efficacy of aerosol therapy with noninvasive ventilator approach (non-invasive ventilation and nasal high flow)
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DOI: 10.1016/j.jddst.2020.101922
Abstract: Abstract Aerosol delivery by nebulizers and pressurized metered-dose inhalers (pMDIs) attached through an adapter or spacer into a ventilation circuit during noninvasive mechanical ventilation (NIV) and high flow nasal cannula (HFNC) add great benefits in… read more here.
Keywords: update efficacy; ventilation; aerosol delivery; high flow ... See more keywords
Effect of different connection adapters on aerosol delivery in invasive ventilation setting; an in-vitro study
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DOI: 10.1016/j.jddst.2020.102177
Abstract: Abstract Introduction Different aerosol generators are used during mechanical ventilation connected to spacers or adapters. The design and volume of these connections can significantly affect aerosol delivery. This study aimed to evaluate the impact of… read more here.
Keywords: aerosol delivery; pmdi; connection; piece ... See more keywords
Aerosolized delivery of ESKAPE pathogens for murine pneumonia models
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DOI: 10.1038/s41598-024-52958-9
Abstract: Murine pneumonia models for ESKAPE pathogens serve to evaluate novel antibacterials or to investigate immunological responses. The majority of published models uses intranasal or to a limited extent the intratracheal instillation to challenge animals. In… read more here.
Keywords: eskape pathogens; murine pneumonia; delivery; aerosol delivery ... See more keywords
Continuous infusion aerosol delivery of prostacyclins during mechanical ventilation: challenges, limitations, and recent advances
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DOI: 10.1080/17425247.2022.2061460
Abstract: ABSTRACT Introduction Critically ill mechanically ventilated patients routinely receive aerosol delivery of epoprostenol by continuous infusion of the nebulizer by syringe pump. This procedure is ‘off-label’ as no FDA approved drug presently exists. Without standardized… read more here.
Keywords: challenges limitations; aerosol delivery; continuous infusion; infusion ... See more keywords
A Trans-Nasal Aerosol Delivery Device for Efficient Pulmonary Deposition.
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DOI: 10.1089/jamp.2016.1333
Abstract: BACKGROUND Efficient delivery of aerosols to the lungs via the nasal route has been difficult to achieve, but it may offer benefits over the traditional oral route for a range of patient populations. Because slow,… read more here.
Keywords: aerosol delivery; trans nasal; delivery; deposition ... See more keywords
Evaluation of host immune responses to Mycobacteriophage Fionnbharth by route of delivery
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DOI: 10.1186/s12985-024-02552-2
Abstract: For much of the last decade, tuberculosis (TB) was the leading cause of mortality due to an infectious pathogen (Mycobacterium tuberculosis, M.tb). Approximately 1.3 million deaths in 2023 worldwide were attributed to TB disease. Focused… read more here.
Keywords: phage; anti phage; delivery; aerosol delivery ... See more keywords
A narrative review on trans-nasal pulmonary aerosol delivery
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DOI: 10.1186/s13054-020-03206-9
Abstract: The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has expanded in recent years. However, various factors influencing aerosol delivery in this setting have not been precisely defined, and no consensus has… read more here.
Keywords: aerosol delivery; nasal pulmonary; trans nasal; delivery ... See more keywords