Nano-in-Microparticles for Aerosol Delivery of Antibiotic-loaded, Fucose-derivatized and Macrophage-targeted Liposomes to Combat Mycobacterial Infections: In Vitro deposition, Pulmonary Barrier Interactions and Targeted Delivery.
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DOI: 10.1002/adhm.202102117
Abstract: XXXX This article is protected by copyright. All rights reserved. read more here.
Keywords: delivery antibiotic; delivery; antibiotic loaded; aerosol delivery ... See more keywords
Efficient Nose-to-Lung Aerosol Delivery with an Inline DPI Requiring Low Actuation Air Volume
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DOI: 10.1007/s11095-018-2473-7
Abstract: PurposeTo demonstrate efficient aerosol delivery through an in vitro nasal model using a dry powder inhaler (DPI) requiring low actuation air volumes (LV) applied during low-flow nasal cannula (LFNC) therapy.MethodsA previously developed LV-DPI was connected… read more here.
Keywords: aerosol delivery; system; delivery; dpi requiring ... See more keywords
Nebulizers and spacers for aerosol delivery through adult nasal cannula at low oxygen flow rate: An in-vitro study
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DOI: 10.1016/j.jddst.2017.04.014
Abstract: Abstract Combining oxygen therapy with aerosol delivery within High flow nasal cannula oxygen therapy (HFNC) is an attractive practice. Delivered dose (DD) was found to decrease with increasing gas flow rates and with smaller sized… read more here.
Keywords: oxygen; aerosol delivery; low oxygen; oxygen flow ... See more keywords
Update efficacy of aerosol therapy with noninvasive ventilator approach (non-invasive ventilation and nasal high flow)
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DOI: 10.1016/j.jddst.2020.101922
Abstract: Abstract Aerosol delivery by nebulizers and pressurized metered-dose inhalers (pMDIs) attached through an adapter or spacer into a ventilation circuit during noninvasive mechanical ventilation (NIV) and high flow nasal cannula (HFNC) add great benefits in… read more here.
Keywords: update efficacy; ventilation; aerosol delivery; high flow ... See more keywords
Effect of different connection adapters on aerosol delivery in invasive ventilation setting; an in-vitro study
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DOI: 10.1016/j.jddst.2020.102177
Abstract: Abstract Introduction Different aerosol generators are used during mechanical ventilation connected to spacers or adapters. The design and volume of these connections can significantly affect aerosol delivery. This study aimed to evaluate the impact of… read more here.
Keywords: aerosol delivery; pmdi; connection; piece ... See more keywords
Continuous infusion aerosol delivery of prostacyclins during mechanical ventilation: challenges, limitations, and recent advances
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DOI: 10.1080/17425247.2022.2061460
Abstract: ABSTRACT Introduction Critically ill mechanically ventilated patients routinely receive aerosol delivery of epoprostenol by continuous infusion of the nebulizer by syringe pump. This procedure is ‘off-label’ as no FDA approved drug presently exists. Without standardized… read more here.
Keywords: challenges limitations; aerosol delivery; continuous infusion; infusion ... See more keywords
A Trans-Nasal Aerosol Delivery Device for Efficient Pulmonary Deposition.
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DOI: 10.1089/jamp.2016.1333
Abstract: BACKGROUND Efficient delivery of aerosols to the lungs via the nasal route has been difficult to achieve, but it may offer benefits over the traditional oral route for a range of patient populations. Because slow,… read more here.
Keywords: aerosol delivery; trans nasal; delivery; deposition ... See more keywords
A narrative review on trans-nasal pulmonary aerosol delivery
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DOI: 10.1186/s13054-020-03206-9
Abstract: The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has expanded in recent years. However, various factors influencing aerosol delivery in this setting have not been precisely defined, and no consensus has… read more here.
Keywords: aerosol delivery; nasal pulmonary; trans nasal; delivery ... See more keywords
Position of different nebulizer types for aerosol delivery in an adult model of mechanical ventilation
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DOI: 10.3389/fmed.2022.950569
Abstract: Background The optimal positions of different types of nebulizer for aerosol delivery remain unclear. Methods Three ICU ventilators employing three types of nebulizer were separately connected to a simulated lung to simulate nebulization during invasive… read more here.
Keywords: aerosol delivery; highest aerosol; ventilation; delivery ... See more keywords
Albuterol Delivery Efficiency in a Pediatric Model of Noninvasive Ventilation With a Single-Limb Circuit
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DOI: 10.4187/respcare.06622
Abstract: BACKGROUND: Pediatric patients treated with noninvasive ventilation (NIV) are frequently given aerosol therapy. Limited pediatric data are available on the efficiency of aerosol delivery efficiency. We evaluated the effect of different nebulizers, positions in the… read more here.
Keywords: aerosol delivery; single limb; circuit; efficiency ... See more keywords
In Vitro Model for Analysis of High-Flow Aerosol Delivery During Continuous Nebulization.
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DOI: 10.4187/respcare.10643
Abstract: BACKGROUND To understand the fate of aerosols delivered by high-flow nasal cannula using continuous nebulization, an open-source anatomical model was developed and validated with a modified real-time gamma ratemeter technique. Mass balance defined circuit losses.… read more here.
Keywords: flow; continuous nebulization; aerosol delivery; model ... See more keywords