Articles with "aerosolization" as a keyword



Computational Fluid Dynamics (CFD) Simulations of Spray Drying: Linking Drying Parameters with Experimental Aerosolization Performance

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Published in 2020 at "Pharmaceutical Research"

DOI: 10.1007/s11095-020-02806-y

Abstract: Purpose The purpose of this study was to develop a new computational fluid dynamics (CFD)-based model of the complex transport and droplet drying kinetics within a laboratory-scale spray dryer, and relate CFD-predicted drying parameters to… read more here.

Keywords: aerosolization; fluid dynamics; spray dryer; drying parameters ... See more keywords
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Advancement of a Positive-Pressure Dry Powder Inhaler for Children: Use of a Vertical Aerosolization Chamber and Three-Dimensional Rod Array Interface.

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Published in 2020 at "Pharmaceutical research"

DOI: 10.1007/s11095-020-02889-7

Abstract: PURPOSE Available dry powder inhalers (DPIs) have very poor lung delivery efficiencies in children. The objective of this study was to advance and experimentally test a positive-pressure air-jet DPI for children based on the use… read more here.

Keywords: aerosolization; rod array; array; positive pressure ... See more keywords

Effectiveness of air disinfection by ozonation or hydrogen peroxide aerosolization in dairy environments

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Published in 2019 at "Food Control"

DOI: 10.1016/j.foodcont.2018.10.022

Abstract: Abstract Indoor air of dairy industry acts as a source or vehicle of microbial contamination affecting both food safety and product shelf life. This research focused on both the monitoring of the air microbial load… read more here.

Keywords: ozonation; aerosolization; air; air disinfection ... See more keywords

A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery.

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Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.09.027

Abstract: Aerosolized administration of biopharmaceuticals to the airways is a promising route for nasal and pulmonary drug delivery, but - in contrast to small molecules - little is known about the effects of aerosolization on safety… read more here.

Keywords: aerosolization; drug delivery; delivery; platform ... See more keywords

Aerosolization behavior of prokaryotes and fungi during composting of vegetable waste.

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Published in 2019 at "Waste management"

DOI: 10.1016/j.wasman.2019.04.008

Abstract: Aerobic composting is one of the most effective ways to treat biowaste. However, microorganisms, including prokaryotes (i.e. bacteria and archaea) and fungi, are inevitably released from the compost as bioaerosols during biowaste composting. The release… read more here.

Keywords: vegetable waste; compost; aerosolization behavior; aerosolization ... See more keywords

Microfluidic Platform Enables Shearless Aerosolization of Lipid Nanoparticles for mRNA Inhalation.

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Published in 2024 at "ACS nano"

DOI: 10.1021/acsnano.4c00768

Abstract: Leveraging the extensive surface area of the lungs for gene therapy, the inhalation route offers distinct advantages for delivery. Clinical nebulizers that employ vibrating mesh technology are the standard choice for converting liquid medicines into… read more here.

Keywords: mrna inhalation; aerosolization; inhalation; aerosolized nanoparticles ... See more keywords

Taxon-specific aerosolization of bacteria and viruses in an experimental ocean-atmosphere mesocosm

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-04409-z

Abstract: Ocean-derived, airborne microbes play important roles in Earth’s climate system and human health, yet little is known about factors controlling their transfer from the ocean to the atmosphere. Here, we study microbiomes of isolated sea… read more here.

Keywords: taxon specific; aerosolization; aerosolization bacteria; ocean atmosphere ... See more keywords

Aerosolization of Mycobacterium avium and Mycobacterium abscessus from a household ultrasonic humidifier

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Published in 2018 at "Journal of Medical Microbiology"

DOI: 10.1099/jmm.0.000822

Abstract: Purpose. To measure the aerosolization of Mycobacterium avium subspecies hominissuis and Mycobacterium abscessus subspecies abscessus from ultrasonic humidifiers. Methodology. An ultrasonic humidifier was filled with sterile tap water and inoculated with water‐acclimated cells of either… read more here.

Keywords: aerosolization; mycobacterium; abscessus; avium ... See more keywords

Aerosolization of Mycobacterium chelonae from heater-cooler-devices: a continuing risk of exposure during cardiac surgery

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Published in 2025 at "Antimicrobial Resistance and Infection Control"

DOI: 10.1186/s13756-025-01635-1

Abstract: Following identification of widespread Mycobacterium chimaera infections in 2013 associated with aerosolization from Sorin heater-cooler-devices (HCD), microbiological monitoring of HCDs has become mandatory in Switzerland. Since 01/2016, four Maquet HCU40 (Getinge) HCDs have been in… read more here.

Keywords: chelonae; mycobacterium; air; aerosolization ... See more keywords

Chemical Emissions From Heated Vitamin E Acetate—Insights to Respiratory Risks From Electronic Cigarette Liquid Oil Diluents Used in the Aerosolization of Δ9-THC-Containing Products

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Published in 2021 at "Frontiers in Public Health"

DOI: 10.3389/fpubh.2021.765168

Abstract: As of February 18, 2020, the e-cigarette, or vaping, product use associated lung injury (EVALI) outbreak caused the hospitalization of a total of 2,807 patients and claimed 68 lives in the United States. Though investigations… read more here.

Keywords: aerosolization; chemical emissions; cigarette; vitamin acetate ... See more keywords

Influence of Aerosolization on Endothelial Cells for Efficient Cell Deposition in Biohybrid and Regenerative Applications

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Published in 2023 at "Micromachines"

DOI: 10.3390/mi14030575

Abstract: The endothelialization of gas exchange membranes can increase the hemocompatibility of extracorporeal membrane oxygenators and thus become a long-term lung replacement option. Cell seeding on large or uneven surfaces of oxygenator membranes is challenging, with… read more here.

Keywords: cell; cell aerosolization; endothelial cells; aerosolization ... See more keywords