Co-spray drying of hygroscopic kanamycin with the hydrophobic drug rifampicin to improve the aerosolization of kanamycin powder for treating respiratory infections.
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DOI: 10.1016/j.ijpharm.2018.02.026
Abstract: High dose delivery of drugs to the lung using a dry powder inhaler (DPI) is an emerging approach to combat drug-resistant local infections. To achieve this, highly aerosolizable powders are required. We hypothesized that co-spray-drying… read more here.
Keywords: rifampicin; spray drying; aerosolization kanamycin; drug ... See more keywords