Adaptation of Pseudomonas aeruginosa clinical isolates to benzalkonium chloride retards its growth and enhances biofilm production
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DOI: 10.1007/s11033-019-04806-7
Abstract: The increasing percentage of Pseudomonas aeruginosa strains that are resistant to multiple antibiotics is a global problem. The exposure of P. aeruginosa isolates to repeated sub lethal concentrations of biocides in hospitals and communities may… read more here.
Keywords: aeruginosa clinical; clinical isolates; antibiotic resistance; adaptation ... See more keywords
Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation
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DOI: 10.1099/jmm.0.000928
Abstract: Purpose. In the cystic fibrosis (CF) airways, Pseudomonas aeruginosa undergoes diverse physiological changes in response to inflammation, antibiotic pressure, oxidative stress and a dynamic bioavailable nutrient pool. These include loss‐of‐function mutations that result in reduced… read more here.
Keywords: pseudomonas aeruginosa; agmatine accumulation; clinical isolates; aeruginosa clinical ... See more keywords
Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants
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DOI: 10.1128/aac.02165-19
Abstract: Imipenem and imipenem-relebactam MICs were determined for 1,445 Pseudomonas aeruginosa clinical isolates and a large panel of isogenic mutants showing the most relevant mutation-driven β-lactam resistance mechanisms. Imipenem-relebactam showed the highest susceptibility rate (97.3%), followed… read more here.
Keywords: clinical isolates; aeruginosa clinical; imipenem relebactam; imipenem ... See more keywords
Antibacterial Effect of 16 Essential Oils and Modulation of mex Efflux Pumps Gene Expression on Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates: Is Cinnamon a Good Fighter?
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DOI: 10.3390/antibiotics12010163
Abstract: The purpose of the study was to describe the antimicrobial activity of 16 common essential oils (EOs) on multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates, including the determination of the effects on mex efflux pumps gene… read more here.
Keywords: efflux pumps; clinical isolates; pumps gene; aeruginosa clinical ... See more keywords