Encapsulation of Pseudomonas aeruginosa elastase inside the P22 virus‐like particle for controlling enzyme–substrate interactions
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DOI: 10.1002/biot.202200015
Abstract: Controlling interactions between enzymes and interaction partners, such as substrates, is important for applications in cellular biology and molecular biochemistry. A strategy for controlling enzyme access with substrate interaction partners is to exploit encapsulation of… read more here.
Keywords: encapsulation pseudomonas; aeruginosa elastase; pseudomonas aeruginosa; controlling enzyme ... See more keywords
N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
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DOI: 10.1021/acs.jmedchem.0c00584
Abstract: In light of the global antimicrobial-resistance crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of action. It has been shown that Pseudomonas aeruginosa elastase (LasB) and Clostridium histolyticum… read more here.
Keywords: aeruginosa elastase; pseudomonas aeruginosa; antivirulence; clostridium ... See more keywords