Nebulized gentamicin in combination with systemic antibiotics for eradicating early Pseudomonas aeruginosa infection in children with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24254
Abstract: Chronic Pseudomonas aeruginosa (Pa) infection in cystic fibrosis (CF) can be prevented with early eradication treatment. In resource‐constrained environments, low‐cost, off‐label nebulized antibiotics, including intravenous gentamicin solution, are often used for eradication therapy. This study… read more here.
Keywords: cystic fibrosis; pseudomonas aeruginosa; aeruginosa infection; infection ... See more keywords
Risk factors, antimicrobial susceptibility pattern and patient outcomes of Pseudomonas aeruginosa infection: A matched case-control study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of infection and public health"
DOI: 10.1016/j.jiph.2020.11.010
Abstract: BACKGROUND Pseudomonas aeruginosa is a leading nosocomial Gram-negative bacteria associated with prolonged hospitalization, and increased morbidity and mortality. Limited data exist regarding P. aeruginosa infection and outcome in patients managed in intensive care units (ICUs)… read more here.
Keywords: aeruginosa infection; infection; study; case ... See more keywords
Intranasal Delivery of Antigen-Coated Polymer Particles Protects against Pseudomonas aeruginosa Infection.
Sign Up to like & getrecommendations! Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.1c00434
Abstract: Pseudomonas aeruginosa is an opportunistic human pathogen that is intrinsically resistant to multiple antibiotics, causing severe and persistent infections in immunocompromised individuals. This bacterium has been listed as a priority pathogen by the WHO in… read more here.
Keywords: antigen coated; intranasal delivery; pseudomonas aeruginosa; aeruginosa infection ... See more keywords
Electrostatically entrapped colistin liposomes for the treatment of Pseudomonas aeruginosa infection
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2016.1228666
Abstract: Abstract The potential use of liposomes for the pulmonary delivery of colistin has been hindered by their phospholipid membrane permeability resulting in a very low entrapment of colistin in the liposomes. To increase the entrapment… read more here.
Keywords: pseudomonas aeruginosa; aeruginosa infection; colistin; colistin liposomes ... See more keywords
Dapagliflozin‐lowered blood glucose reduces respiratory Pseudomonas aeruginosa infection in diabetic mice
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Pharmacology"
DOI: 10.1111/bph.13741
Abstract: Hyperglycaemia increases glucose concentrations in airway surface liquid and increases the risk of pulmonary Pseudomonas aeruginosa infection. We determined whether reduction of blood and airway glucose concentrations by the anti‐diabetic drug dapagliflozin could reduce P.… read more here.
Keywords: pseudomonas aeruginosa; aeruginosa infection; blood; diabetic mice ... See more keywords
Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00052-22
Abstract: The bacterium Pseudomonas aeruginosa can colonize the airways of patients with chronic lung disease. Within the lung, P. aeruginosa forms biofilms that can enhance resistance to antibiotics and immune defenses. P. aeruginosa biofilm formation is… read more here.
Keywords: lung; glycoside hydrolases; aeruginosa infection; pseudomonas aeruginosa ... See more keywords
A Nonlethal Murine Flame Burn Model Leads to a Transient Reduction in Host Defenses and Enhanced Susceptibility to Lethal Pseudomonas aeruginosa Infection
Sign Up to like & getrecommendations! Published in 2021 at "Infection and Immunity"
DOI: 10.1128/iai.00091-21
Abstract: Of the 486,000 burn injuries that required medical treatment in the United States in 2016, 40,000 people were hospitalized, with >3,000 fatalities. After burn injury, humans are at increased risk of sepsis and mortality from infections… read more here.
Keywords: flame burn; infection; aeruginosa infection; pseudomonas aeruginosa ... See more keywords
Influenza Virus Infection Increases Host Susceptibility To Secondary Infection with Pseudomonas aeruginosa, and This Is Attributed To Neutrophil Dysfunction through Reduced Myeloperoxidase Activity
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03655-22
Abstract: Secondary bacterial infection greatly increased the morbidity and mortality of influenza virus infection. To investigate the underlying mechanism by which influenza impairs the pulmonary defense against secondary Pseudomonas aeruginosa (P. aeruginosa) infection, we established a… read more here.
Keywords: virus infection; infection; aeruginosa infection; activity ... See more keywords
An Outbreak of Pseudomonas Aeruginosa Infection Linked to a “Black Friday” Piercing Event
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Currents"
DOI: 10.1371/currents.outbreaks.51af24797f6f856a9861b5ddabc7db58
Abstract: Introduction Outbreaks linked to cosmetic piercing are rare, but can cause significant illness. We report the investigation and management of a point-source outbreak that occurred during a Black Friday promotional event in North West England.… read more here.
Keywords: pseudomonas aeruginosa; aeruginosa infection; infection; outbreak pseudomonas ... See more keywords
Epigallocatechin-3-gallate ameliorates liver injury secondary to Pseudomonas aeruginosa pneumonia.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.2139/ssrn.4163674
Abstract: Pseudomonas aeruginosa is a dangerous pathogen causing nosocomial pneumonia. P. aeruginosa infection-induced liver damage is another fatal threat, and antibiotic treatment is not effective in relieving P. aeruginosa virulence-triggered damage. We here evaluated the protective… read more here.
Keywords: pneumonia; pseudomonas aeruginosa; epigallocatechin gallate; infection ... See more keywords
Pseudomonas aeruginosa Infection Modulates the Immune Response and Increases Mice Resistance to Cryptococcus gattii
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.811474
Abstract: Cryptococcosis is an invasive mycosis caused by Cryptococcus spp. that affects the lungs and the central nervous system (CNS). Due to the severity of the disease, it may occur concomitantly with other pathogens, as a… read more here.
Keywords: pseudomonas aeruginosa; infection; aeruginosa infection; infection modulates ... See more keywords