Therapeutic approaches for combating Pseudomonas aeruginosa Infections.
Sign Up to like & getrecommendations! Published in 2022 at "Microbes and infection"
DOI: 10.1016/j.micinf.2022.104950
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen responsible for acute hospital-acquired infections. This review described various therapeutic approaches to treat infections caused by P. aeruginosa, including conventional therapy, novel antibiotic treatments and treatments other than antibiotics.… read more here.
Keywords: combating pseudomonas; aeruginosa infections; therapeutic approaches; approaches combating ... See more keywords
The Therapeutic Pipeline for Pseudomonas aeruginosa Infections.
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DOI: 10.1021/acsinfecdis.8b00112
Abstract: Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen, designated by the World Health Organization as a critical priority for development of new therapeutics due to high levels of intrinsic and acquired antibiotic resistance. Other challenges include… read more here.
Keywords: pipeline pseudomonas; pseudomonas aeruginosa; aeruginosa infections; therapeutic pipeline ... See more keywords
Treatment of carbapenem-resistant Pseudomonas aeruginosa infections: a case for cefiderocol
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2022.2071701
Abstract: ABSTRACT Introduction Carbapenem-resistant (CR) Pseudomonas aeruginosa infections constitute a serious clinical threat globally. Patients are often critically ill and/or immunocompromised. Antibiotic options are limited and are currently centered on beta-lactam–beta-lactamase inhibitor (BL–BLI) combinations and the… read more here.
Keywords: treatment; aeruginosa infections; carbapenem resistant; cefiderocol ... See more keywords
Multisite Pseudomonas aeruginosa Infections Detected by Metagenomic Next-Generation Sequencing in a Child with Aplastic Anemia: A Case Report.
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DOI: 10.1093/labmed/lmab123
Abstract: Microbial cultivation is the current gold standard for the clinical diagnosis of bacterial infections. However, this method sometimes produces false negative results. We present a case study of multisite Pseudomonas aeruginosa infections detected by metagenomic… read more here.
Keywords: aeruginosa infections; pseudomonas aeruginosa; infections detected; detected metagenomic ... See more keywords
Skin manifestations of Pseudomonas aeruginosa infections.
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000717
Abstract: PURPOSE OF REVIEW Pseudomonas aeruginosa is an opportunistic pathogen with considerable morbidity and mortality, particularly in vulnerable hosts. Skin manifestations are common, either representing local inoculation or secondary skin seeding following bloodstream infections. As patients… read more here.
Keywords: epidemiology; aeruginosa infections; skin manifestations; pseudomonas aeruginosa ... See more keywords
Clinical Pharmacology of Bacteriophage Therapy: A Focus on Multidrug-Resistant Pseudomonas aeruginosa Infections
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DOI: 10.3390/antibiotics10050556
Abstract: Pseudomonas aeruginosa is one of the most common causes of healthcare-associated diseases and is among the top three priority pathogens listed by the World Health Organization (WHO). This Gram-negative pathogen is especially difficult to eradicate… read more here.
Keywords: pseudomonas aeruginosa; aeruginosa infections; pharmacology; multidrug resistant ... See more keywords
Potential Therapeutic Targets for Combination Antibody Therapy against Pseudomonas aeruginosa Infections
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DOI: 10.3390/antibiotics10121530
Abstract: Despite advances in antimicrobial therapy and even the advent of some effective vaccines, Pseudomonas aeruginosa (P. aeruginosa) remains a significant cause of infectious disease, primarily due to antibiotic resistance. Although P. aeruginosa is commonly treatable… read more here.
Keywords: aeruginosa infections; therapeutic targets; aeruginosa; drug ... See more keywords
Azithromycin: An Underappreciated Quinolone-Sparing Oral Treatment for Pseudomonas aeruginosa Infections
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DOI: 10.3390/antibiotics11040515
Abstract: Outpatient treatment of Pseudomonas aeruginosa infections is challenged by increasing rates of resistance to fluoroquinolones, the only class of antibiotics which offers an established oral route of administration against this organism. Azithromycin does not demonstrate… read more here.
Keywords: pseudomonas aeruginosa; aeruginosa infections; azithromycin underappreciated; treatment ... See more keywords
The In Vivo and In Vitro Assessment of Pyocins in Treating Pseudomonas aeruginosa Infections
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DOI: 10.3390/antibiotics11101366
Abstract: Pseudomonas aeruginosa can cause several life-threatening infections among immunocompromised patients (e.g., cystic fibrosis) due to its ability to adapt and develop resistance to several antibiotics. In recent years, P. aeruginosa infections has become difficult to… read more here.
Keywords: aeruginosa infections; vitro assessment; pseudomonas aeruginosa; aeruginosa strains ... See more keywords
Overcoming Barriers to Preventing and Treating P. aeruginosa Infections Using AAV Vectored Immunoprophylaxis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123162
Abstract: Pseudomonas aeruginosa is a bacterial pathogen of global concern and is responsible for 10–15% of nosocomial infections worldwide. This opportunistic bacterial pathogen is known to cause serious complications in immunocompromised patients and is notably the… read more here.
Keywords: aeruginosa infections; aav; preventing treating; barriers preventing ... See more keywords