Aesculetin Suppresses Airway Epithelial Barrier Disruption Induced by Inhalation of Urban Coarse Particulate: Involvement of Neutrophil Elastase and Protease-Activated Receptor‑2
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DOI: 10.1021/acsomega.5c02198
Abstract: Particulate matter (PM) is a mixture of solid and liquid air pollutants floating in the air, and it is the most harmful form of air pollutant because it can penetrate deep into the lungs and… read more here.
Keywords: aesculetin; epithelial barrier; barrier; airway epithelial ... See more keywords
Aesculetin exhibited anti-inflammatory activities through inhibiting NF-кB and MAPKs pathway in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4019139
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Aesculetin (6,7-dihydroxy-2H-1-benzopyran-2-one) has been reported to exhibit potent anti-inflammatory property both in vitro and in vivo. AIMS OF THIS STUDY In this study, we evaluated the anti-inflammatory effect and investigated underlying molecular mechanisms… read more here.
Keywords: vitro vivo; aesculetin; dss induced; mapks ... See more keywords