Articles with "af10 mll" as a keyword



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Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia

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Published in 2021 at "Leukemia"

DOI: 10.1038/s41375-021-01244-y

Abstract: Chromosome translocations involving the MLL gene are common rearrangements in leukemia. Such translocations fuse the MLL 5’-region to partner genes in frame, producing MLL-fusions that cause MLL-related leukemia. MLL-fusions activate transcription of target genes such… read more here.

Keywords: mll enl; af10 mll; leukemia; mll ... See more keywords