Increased lncRNA AFAP1‐AS1 expression predicts poor prognosis in gastric cancer: Evidence from published studies and followed up verification
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5287
Abstract: The purpose of this study was to clarify the influence of long non‐coding RNA actin fiber‐associated protein‐1 antisense RNA 1 (lncRNA AFAP1‐AS1) on the prognosis of gastric cancer (GC). read more here.
Keywords: lncrna afap1; prognosis gastric; gastric cancer; afap1 as1 ... See more keywords
LncRNA AFAP1-AS1 contributes to the progression of endometrial carcinoma by regulating miR-545-3p/VEGFA pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2020.101606
Abstract: Endometrial carcinoma (EC) accounts for 20%-30% of female reproductive tumors. Targeted therapy for EC has shown great advantages with small side effects. To improve the survival of EC patients, more new therapeutic targets need to… read more here.
Keywords: afap1 as1; endometrial carcinoma; lncrna afap1; mir 545 ... See more keywords
AFAP1-AS1/Hsa-miR-15a-5p/Bcl-2 Axis is a Potential Regulator of Cancer Cell Proliferation and Apoptosis in Gallbladder Carcinoma
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DOI: 10.1080/01635581.2022.2059090
Abstract: Abstract Objective Gallbladder carcinoma (GBC) is a common malignancy of the biliary tract that, with late diagnosis, is often fatal. A better understanding of the underlying molecular mechanisms may facilitate targeted therapy for GBC. Therefore,… read more here.
Keywords: apoptosis; proliferation; mir 15a; hsa mir ... See more keywords
Long non-coding ribonucleic acid AFAP1-AS1 promotes chondrocyte proliferation via the miR-512-3p/matrix metallopeptidase 13 (MMP-13) axis
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DOI: 10.1080/21655979.2022.2031390
Abstract: ABSTRACT Long-chain non-coding RNAs are reported to be involved in cartilage damage. However, less research on the role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) in osteoarthritis. To investigate AFAP1-AS1 function in osteoarthritis… read more here.
Keywords: afap1 as1; mir 512; chondrocyte proliferation; expression ... See more keywords
AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1
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DOI: 10.1080/21655979.2022.2033464
Abstract: ABSTRACT The oncogenic role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) has been reported in retinoblastoma (RB). However, the underlying regulatory mechanisms remain poorly understood. In this study, reverse transcription-quantitative polymerase chain reaction… read more here.
Keywords: gnb1; afap1 as1; mir 545; migration ... See more keywords
The knockdown of LncRNA AFAP1-AS1 suppressed cell proliferation, migration, and invasion, and promoted apoptosis by regulating miR-545-3p/hepatoma-derived growth factor axis in lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001003
Abstract: Supplemental Digital Content is available in the text. Lung cancer is one of the most common human cancers. Long noncoding RNA AFAP1-AS1 (LncRNA AFAP1-AS1) and microRNA-545-3p (miR-545-3p) were reported to play important roles in lung… read more here.
Keywords: afap1 as1; hdgf; lung cancer; cancer ... See more keywords
High expression of AFAP1-AS1 is associated with poor prognosis of digestive system cancers: A meta-analysis
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DOI: 10.1097/md.0000000000030833
Abstract: Background: Actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) is associated with prognosis in many cancers. The aim of this study was to systematically evaluate the potential correlation between AFAP1-AS1 and the prognosis of digestive… read more here.
Keywords: expression afap1; prognosis; high expression; afap1 as1 ... See more keywords
Long noncoding RNA actin filament‐associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine‐specific demethylase 1 and repressing HMG box‐containing protein 1 in non‐small‐cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.14039
Abstract: The number of documented long noncoding RNAs (lncRNAs) has dramatically increased, and their biological functions and underlying mechanisms in pathological processes, especially cancer, remain to be elucidated. Actin filament‐associated protein 1 antisense RNA 1 (AFAP1‐AS1)… read more here.
Keywords: cancer; afap1 as1; rna; cell ... See more keywords
Upregulation of the long non-coding RNA AFAP1-AS1 affects the proliferation, invasion and survival of tongue squamous cell carcinoma via the Wnt/β-catenin signaling pathway
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DOI: 10.1186/s12943-017-0752-2
Abstract: BackgroundLong non-coding RNA (lncRNA) actin filament associated protein 1 antisense RNA1 (AFAP1-AS1) is oriented in an antisense direction to the protein-coding gene AFAP1 in the opposite strand. Previous studies showed that lncRNA AFAP1-AS1 was upregulated… read more here.
Keywords: tscc; afap1 as1; rna; as1 ... See more keywords
LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells
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DOI: 10.18632/oncotarget.16880
Abstract: We investigated the role of actin filament associated protein 1 antisense RNA1 (AFAP1-AS1) lncRNA in promoting cholangiocarcinoma (CCA). qRT-PCR analysis of patient samples showed that AFAP1-AS1 expression was higher in CCA tumors than matched adjacent… read more here.
Keywords: afap1 as1; as1 knockdown; as1; cca ... See more keywords
Meta-analysis of the prognostic value of long non-coding RNA AFAP1-AS1 for cancer patients in China
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DOI: 10.18632/oncotarget.23568
Abstract: LncRNA actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) is often dysregulated in cancer. We performed this meta-analysis to clarify the usefulness of AFAP1-AS1 as a prognostic marker in malignant tumors. The PubMed, Medline, OVID,… read more here.
Keywords: rna afap1; afap1 as1; afap1; high afap1 ... See more keywords