Curcumin confers hepatoprotection against AFB1-induced toxicity via activating autophagy and ameliorating inflammation involving Nrf2/HO-1 signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4323-4
Abstract: The current study demonstrated curcumin intervention against AFB1-indeuced hepatotoxicity. The hallmarks of autophagy and inflammation were assessed by transmission electron microscopy, RT-PCR and western blot. Besides, normal cellular morphology, autophagosomes were found in control and… read more here.
Keywords: involving nrf2; inflammation; inflammation involving; nrf2 signaling ... See more keywords
Curcumin protects against Aflatoxin B1-induced liver injury in broilers via the modulation of long non-coding RNA expression.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111725
Abstract: Aflatoxin B1 (AFB1) is a potent hepatotoxic and carcinogenic agent. Curcumin possesses potential anti-inflammatory, anti-oxidative and hepatoprotective effects. However, the role of LncRNAs in the protective mechanisms of curcumin against AFB1-induced liver damage is still… read more here.
Keywords: group; afb1 induced; expression; induced liver ... See more keywords
Protective effects of lycopene against AFB1-induced erythrocyte dysfunction and oxidative stress in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2020.01.015
Abstract: To evaluate the protective role of lycopene (LYC) against aflatoxin B1 (AFB1)-induced erythrocyte dysfunction and oxidative stress, male kunming mice were treated with LYC (5 mg/kg) and/or AFB1 (0.75 mg/kg) by intragastric administration for 30 d. Hematological… read more here.
Keywords: afb1 induced; induced erythrocyte; erythrocyte dysfunction; oxidative stress ... See more keywords
IgY Reduces AFB1-Induced Cytotoxicity, Cellular Dysfunction, and Genotoxicity in Human L-02 Hepatocytes and Swan 71 Trophoblasts.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b05385
Abstract: Aflatoxin B1 (AFB1) causes hepatotoxic, genotoxic, and immunotoxic effects in a variety of species. Although various neutralizing agents of AFB1 toxicity have been studied, the egg yolk immunoglobulin (IgY) detoxification of small molecular toxins and… read more here.
Keywords: afb1; afb1 igy; afb1 induced; induced cytotoxicity ... See more keywords
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2129672
Abstract: This study was conducted to investigate the protective potential of a pharmaceutically formulated capsule of artichoke leaf powder (ArLP) against aflatoxin B1 (AFB1)-induced hepatotoxicity in male albino rats. In the 42-day experiment, rats were divided… read more here.
Keywords: characterized extract; afb1 induced; effects chemically; chemically characterized ... See more keywords
Gallic acid protects against Aflatoxin B1 -induced oxidative and inflammatory stress damage in rats kidneys and liver.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13316
Abstract: The adverse effect of Aflatoxin B1 (AFB1 ) exposure in both humans and rodents has been widely reported. The beneficial health effects of gallic acid (GA) against AFB1 -induced toxicity in vitro have been published.… read more here.
Keywords: gallic acid; inflammatory; afb1 induced; stress ... See more keywords
Caffeic acid mitigates aflatoxin B1-mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and the redox-regulatory systems.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14090
Abstract: Aflatoxin B1 (AFB1 ) is a toxic metabolite of public health concern. The present study investigates the protective effects of caffeic acid (CA) against AFB1 -induced oxidative stress, inflammation, and apoptosis in the hypothalamus, epididymis,… read more here.
Keywords: caffeic acid; male; rats coexposed; toxicity ... See more keywords
Water‐soluble substances of wheat: a potential preventer of aflatoxin B1‐induced liver damage in broilers
Sign Up to like & getrecommendations! Published in 2019 at "Poultry Science"
DOI: 10.3382/ps/pey358
Abstract: &NA; Aflatoxin B1 (AFB1) is very harmful for broiler production and public health. The water‐soluble castoff in gluten production, i.e., the water‐soluble substances of wheat (WSW) that contains 14% pentosan has positive effect on animal… read more here.
Keywords: water soluble; afb1 induced; liver damage; afb1 ... See more keywords
Effect of Curcumin as Feed Supplement on Immune Response and Pathological Changes of Broilers Exposed to Aflatoxin B1
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12091188
Abstract: In this study, we examined the protective effects of curcumin against the AFB1-induced immune response of and pathological changes in broilers. Histopathology examinations showed that at day 28, AFB1 (5 mg/kg) exposure leads to severe… read more here.
Keywords: afb1 induced; response pathological; immune response; pathological changes ... See more keywords
AFB1 Induced Transcriptional Regulation Related to Apoptosis and Lipid Metabolism in Liver of Chicken
Sign Up to like & getrecommendations! Published in 2020 at "Toxins"
DOI: 10.3390/toxins12050290
Abstract: Aflatoxin B1 (AFB1) leads to a major risk to poultry and its residues in meat products can also pose serious threat to human health. In this study, after feeding 165-day-old Roman laying hens for 35… read more here.
Keywords: afb1; apoptosis; afb1 induced; expression ... See more keywords