ERK2 Mutations Affect Interactions, Localization, and Dimerization.
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DOI: 10.1021/acs.biochem.3c00044
Abstract: The most frequent ERK2 (MAPK1) mutation in cancers, E322K, lies in the common docking (CD) site, which binds short motifs made up of basic and hydrophobic residues present in the activators MEK1 (MAP2K1) and MEK2… read more here.
Keywords: erk2 mutations; mutations affect; affect interactions; dimerization ... See more keywords