Substrate viscoelasticity affects human macrophage morphology and phagocytosis.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01683d
Abstract: Viscoelasticity is an inherent characteristic of many living tissues and, in an attempt to better recapitulate this aspect in cell culture, hydrogel biomaterials have been engineered to exhibit time-dependent energy-dissipative mechanical behavior. Viscoelastic hydrogel culture… read more here.
Keywords: viscoelasticity; affects human; substrate viscoelasticity; phagocytosis ... See more keywords
WIP deficiency severely affects human lymphocyte architecture during migration and synapse assembly.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-04-777383
Abstract: To the editor: The high motility of immune cells and their ability to establish cell-to-cell contacts depend on a tight regulation of actin cytoskeleton dynamics. Murine studies have identified the Wiskott-Aldrich syndrome protein (WASP)-interacting protein… read more here.
Keywords: deficiency severely; wip deficiency; severely affects; lymphocyte architecture ... See more keywords
Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch
Sign Up to like & getrecommendations! Published in 2020 at "BMC Immunology"
DOI: 10.1186/s12865-020-0342-8
Abstract: Hypoxia is a potent molecular signal for cellular metabolism, mitochondrial function, and migration. Conditions of low oxygen tension trigger regulatory cascades mediated via the highly conserved HIF-1 α post-translational modification system. In the adaptive immune… read more here.
Keywords: switch; migration; directly affects; affects human ... See more keywords