Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats
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DOI: 10.1002/nau.22920
Abstract: Kv7 voltage‐gated potassium channels have been suggested to modulate mechano‐afferent transduction and nociception in the bladder. We investigated the effects of retigabine, a Kv7 channel activator, on rhythmic bladder contractions (RBCs), and single‐unit afferent activities… read more here.
Keywords: channel activator; bladder; retigabine kv7; kv7 channel ... See more keywords
Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction
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DOI: 10.1002/nau.23547
Abstract: We investigated the effects of silodosin, an α1A‐adrenoceptor (AR) antagonist, on bladder function, especially on non‐voiding contractions (NVCs), in a male rat model of bladder outlet obstruction (BOO) by evaluating cystometry (CMG) findings and bladder… read more here.
Keywords: bladder; effects silodosin; outlet obstruction; afferent activities ... See more keywords
Characteristics of the mechanosensitive bladder afferent activities in relation with microcontractions in male rats with bladder outlet obstruction
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DOI: 10.1038/s41598-017-07898-y
Abstract: We investigated the characteristics of bladder mechanosensitive single-unit afferent activities (SAAs) in rats with a bladder outlet obstruction (BOO) and their relationship with bladder microcontractions. Male Wistar rats were divided into Sham and BOO groups.… read more here.
Keywords: bladder; outlet obstruction; afferent activities; rats bladder ... See more keywords