Affibody Molecules in Biotechnological and Medical Applications.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2017.04.007
Abstract: Affibody molecules are small (6.5-kDa) affinity proteins based on a three-helix bundle domain framework. Since their introduction 20 years ago as an alternative to antibodies for biotechnological applications, the first therapeutic affibody molecules have now… read more here.
Keywords: biotechnological medical; affibody; affibody molecules; molecules biotechnological ... See more keywords
Novel Affibody Molecules Specifically Bind to SARS-CoV-2 Spike Protein and Efficiently Neutralize Delta and Omicron Variants
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03562-22
Abstract: SARS-CoV-2 and its variants are threatening the whole world. Although a full dose of vaccine injection showed great preventive effects and monoclonal antibody reagents have also been used for a specific treatment, the global pandemic… read more here.
Keywords: novel affibody; rbmfp; affibody molecules; affibody ... See more keywords
Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Cell Factories"
DOI: 10.1186/s12934-022-01761-0
Abstract: Background Affibody molecules are synthetic peptides with a variety of therapeutic and diagnostic applications. To date, Affibody molecules have mainly been produced by the bacterial production host Escherichia coli. There is an interest in exploring… read more here.
Keywords: affibody molecules; saccharomyces cerevisiae; secretion; affibody ... See more keywords
Construction and Validation of a New Naïve Sequestrin Library for Directed Evolution of Binders against Aggregation-Prone Peptides
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010836
Abstract: Affibody molecules are small affinity proteins that have excellent properties for many different applications, ranging from biotechnology to diagnostics and therapy. The relatively flat binding surface is typically resulting in high affinity and specificity when… read more here.
Keywords: high affinity; affinity; validation new; affibody molecules ... See more keywords