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   Articles with "affibody molecules" as a keyword



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Affibody Molecules in Biotechnological and Medical Applications.

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recommendations! Published in 2017 at "Trends in biotechnology"

DOI: 10.1016/j.tibtech.2017.04.007

Abstract: Affibody molecules are small (6.5-kDa) affinity proteins based on a three-helix bundle domain framework. Since their introduction 20 years ago as an alternative to antibodies for biotechnological applications, the first therapeutic affibody molecules have now… read more here.

Keywords: biotechnological medical; affibody; affibody molecules; molecules biotechnological ... See more keywords

DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-024-84574-y

Abstract: A distinctive feature of both type 1 and type 2 diabetes is the waning of insulin-secreting beta cells in the pancreas. New methods for direct and specific targeting of the beta cells could provide platforms… read more here.

Keywords: affibody; delivery; imaging reagents; beta ... See more keywords

Novel Affibody Molecules Specifically Bind to SARS-CoV-2 Spike Protein and Efficiently Neutralize Delta and Omicron Variants

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recommendations! Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03562-22

Abstract: SARS-CoV-2 and its variants are threatening the whole world. Although a full dose of vaccine injection showed great preventive effects and monoclonal antibody reagents have also been used for a specific treatment, the global pandemic… read more here.

Keywords: novel affibody; rbmfp; affibody molecules; affibody ... See more keywords

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

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recommendations! Published in 2022 at "Microbial Cell Factories"

DOI: 10.1186/s12934-022-01761-0

Abstract: Background Affibody molecules are synthetic peptides with a variety of therapeutic and diagnostic applications. To date, Affibody molecules have mainly been produced by the bacterial production host Escherichia coli. There is an interest in exploring… read more here.

Keywords: affibody molecules; saccharomyces cerevisiae; secretion; affibody ... See more keywords

Construction and Validation of a New Naïve Sequestrin Library for Directed Evolution of Binders against Aggregation-Prone Peptides

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24010836

Abstract: Affibody molecules are small affinity proteins that have excellent properties for many different applications, ranging from biotechnology to diagnostics and therapy. The relatively flat binding surface is typically resulting in high affinity and specificity when… read more here.

Keywords: high affinity; affinity; validation new; affibody molecules ... See more keywords