TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation
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DOI: 10.1093/toxsci/kfx215
Abstract: FICZ and TCDD, two high-affinity AhR ligands, are reported to have opposite effects on T cell differentiation with TCDD inducing regulatory T cells and FICZ inducing Th17 cells. This dichotomy has been attributed to ligand-intrinsic… read more here.
Keywords: affinity ahr; high affinity; cell differentiation; ahr ligands ... See more keywords