684 A low affinity bivalent mesothelin-binding MATCH4 multispecific T cell engager increases cytotoxic selectivity for high mesothelin expressing cells
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DOI: 10.1136/jitc-2020-sitc2020.0684
Abstract: Background The effective treatment of solid tumors remains an unmet medical need. Several concepts exist to treat malignancies, including antibody-drug or -immunotoxin conjugates, immune checkpoint inhibition, CAR- T cells, as well as bispecific T cell… read more here.
Keywords: affinity; affinity bivalent; low affinity; cell ... See more keywords