Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes
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DOI: 10.3390/molecules29102272
Abstract: L-asparaginases are used in the treatment of acute lymphoblastic leukemia. The aim of this work was to compare the antiproliferative potential and proapoptotic properties of novel L-asparaginases from different structural classes, viz. EcAIII and KpAIII… read more here.
Keywords: crucial therapeutic; ecaii; cell; affinity crucial ... See more keywords