LAUSR

Affinity-Directed Dynamics of Host-Guest Motifs for Pharmacokinetic Modulation via Supramolecular PEGylation.

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0 Published in 2021 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.1c00648

Abstract: Proteins are an impactful class of therapeutics but can exhibit suboptimal therapeutic performance, arising from poor control over the timescale of clearance. Covalent PEGylation is one established strategy to extend circulation time but often at… read more here.

Keywords: pegylation; host guest; supramolecular pegylation; directed dynamics ... See more keywords