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In silicopost-SELEX screening and experimental characterizations for acquisition of high affinity DNA aptamers against carcinoembryonic antigen

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0 Published in 2019 at "RSC Advances"

DOI: 10.1039/c8ra10163a

Abstract: High affinity DNA aptamers against carcinoembryonic antigen were selected and verified by using anin silicoapproach and experimental characterizations. read more here.

Keywords: carcinoembryonic antigen; dna aptamers; experimental characterizations; affinity dna ... See more keywords

Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding

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2 Published in 2023 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkad015

Abstract: Abstract The DNA mismatch repair protein MutSα recognizes wrongly incorporated DNA bases and initiates their correction during DNA replication. Dysfunctions in mismatch repair lead to a predisposition to cancer. Here, we study the homozygous mutation… read more here.

Keywords: mismatch binding; affinity dna; dna; high affinity ... See more keywords

Construction of an Immunosensor Based on the Affinity DNA Functional Ligands to the Fc Segment of IgG Antibody

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0 Published in 2025 at "Biosensors"

DOI: 10.3390/bios15110747

Abstract: Over the past few decades, Fc fragment-conjugated proteins, such as Protein A, have been extensively utilized across a range of applications, including antibody purification, site-specific immobilization of antibodies, and the development of biosensing platforms. In… read more here.

Keywords: dna functional; antibody; affinity; affinity dna ... See more keywords