Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate
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DOI: 10.1080/2162402x.2018.1532759
Abstract: ABSTRACT Circulating T-cells that have passed thymic selection generally bear T-cell receptors (TCRs) with sub-optimal affinity for cancer-associated antigens, resulting in a limited ability to detect and eliminate tumor cells. Engineering TCRs to increase their… read more here.
Keywords: affinity enhanced; cell receptors; strategy; mage a10 ... See more keywords