NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization
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DOI: 10.1128/mcb.00424-16
Abstract: ABSTRACT Antigen-specific adhesion between T cells and antigen-presenting cells (APC) during the formation of the immunological synapse (IS) is mediated by LFA-1 and ICAM-1. Here, LFA-1–ICAM-1 interactions were measured at the single-molecule level on supported… read more here.
Keywords: synapse; high affinity; affinity lfa; organization ... See more keywords