Regulation by metal ions and the ADMIDAS of integrin α5β1 conformational states and intrinsic affinities.
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DOI: 10.1091/mbc.e21-11-0536
Abstract: Activation of integrins by Mn2+ is a benchmark in the integrin field, but how it works and whether it reproduces physiologic activation is unknown. We show that Mn2+ and high Mg2+ concentrations compete with Ca2+… read more here.
Keywords: affinity open; metal ions; affinity; intrinsic affinities ... See more keywords