Structure-Activity Relationship Studies to Identify Affinity Probes in Bis-aryl Sulfonamides that Prolong Immune Stimuli.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00870
Abstract: Agents that safely induce, enhance, or sustain multiple innate immune signaling pathways could be developed as potent vaccine adjuvants or co-adjuvants. Using high-throughput screens with cell-based nuclear factor kappa B (NF-κB) and interferon stimulating response… read more here.
Keywords: affinity probes; bis aryl; affinity; activity relationship ... See more keywords
Affinity probes based on small-molecule inhibitors for tumor imaging
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1028493
Abstract: Methods for molecular imaging of target areas, including optical imaging, radionuclide imaging, magnetic resonance imaging and other imaging technologies, are helpful for the early diagnosis and precise treatment of cancers. In addition to cancer management,… read more here.
Keywords: molecule inhibitors; small molecule; affinity; probes based ... See more keywords