Association of early-onset Alzheimer’s disease with germline-generated high affinity self-antigen load
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DOI: 10.1038/s41398-020-0826-6
Abstract: Self-antigen presentation outside the central nervous system has crucial role regarding self-proteins tolerance and autoimmunity, leading to neuroinflammation. Self-antigen with strong-binding affinity is considered to be pathogenic. We aim to investigate whether strong-binding affinity self-antigen… read more here.
Keywords: onset; antigen load; affinity self; self antigen ... See more keywords