Articles with "affinity small" as a keyword



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Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.

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Published in 2022 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.2c01421

Abstract: A series of small-molecule YEATS4 binders have been discovered as part of an ongoing research effort to generate high-quality probe molecules for emerging and/or challenging epigenetic targets. Analogues such as 4d and 4e demonstrate excellent… read more here.

Keywords: small molecule; yeats4; high affinity; affinity small ... See more keywords