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Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles

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Published in 2019 at "Translational Oncology"

DOI: 10.1016/j.tranon.2019.04.019

Abstract: Gastrointestinal toxicity is a frequently observed adverse event during cancer treatment with traditional chemotherapeutics. Currently, traditional chemotherapeutics are often combined with targeted biologic agents. These biologics, however, possess a distinct toxicity profile, and they may… read more here.

Keywords: week; metabolic changes; treatment; aflibercept erlotinib ... See more keywords