A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma.
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DOI: 10.1101/gr.227181.117
Abstract: Pre-mRNA splicing can contribute to the switch of cell identity that occurs in carcinogenesis. Here, we analyze a large collection of RNA-seq data sets and report that splicing changes in hepatocyte-specific enzymes, such as AFMID… read more here.
Keywords: recurrence; afmid isoforms; switch; switch alternatively ... See more keywords