Combination of serum paraoxonase/arylesterase 1 and antithrombin-III is a promising non-invasion biomarker for discrimination of AFP-negative HCC versus liver cirrhosis patients.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.11.013
Abstract: OBJECTIVE α-fetoprotein is often used in the diagnosis of hepatocellular carcinoma (HCC). However, there are currently less efficient and highly specific biomarkers to distinguish AFP-negative HCC from liver cirrhosis (LC) patients. PATIENTS AND METHODS We… read more here.
Keywords: cirrhosis patients; afp negative; hcc; negative hcc ... See more keywords
Nomogram to predict the prognosis of patients with AFP-negative hepatocellular carcinoma undergoing chemotherapy: A SEER based study
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DOI: 10.1097/md.0000000000033319
Abstract: This study aimed to formulate reliable nomograms for predicting the outcomes of α-fetoprotein (AFP)-negative hepatocellular carcinoma (HCC) patients after chemotherapy. HCC patients with normal AFP expression who received chemotherapy were screened and evaluated from the… read more here.
Keywords: hepatocellular carcinoma; negative hepatocellular; afp negative; hcc patients ... See more keywords
Alpha-Fetoprotein (AFP)-Negative Hepatoid Adenocarcinoma of the Stomach and its Associated Uncommon Features With a Review.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of surgical pathology"
DOI: 10.1177/10668969221142038
Abstract: Hepatoid adenocarcinoma of the stomach is a rare histologic subtype of gastric carcinoma. Morphologically, it shows hepatocyte-like features and the tumor cells can show the expression of alpha-fetoprotein (AFP) in the tumor cells as well… read more here.
Keywords: adenocarcinoma stomach; negative hepatoid; afp negative; hepatoid adenocarcinoma ... See more keywords
Prediction of survival and analysis of prognostic factors for patients with AFP negative hepatocellular carcinoma: a population-based study
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DOI: 10.1186/s12876-024-03185-z
Abstract: Purpose Hepatocellular carcinoma (HCC) has a poor prognosis, and alpha-fetoprotein (AFP) is widely used to evaluate HCC. However, the proportion of AFP-negative individuals cannot be disregarded. This study aimed to establish a nomogram of risk… read more here.
Keywords: value; analysis; afp negative; patients afp ... See more keywords
Molecular differences between AFP-negative and AFP-positive hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e15681
Abstract: e15681 Background: Alpha-fetoprotein (AFP) is a major biomarker for diagnosis of hepatocellular carcinoma (HCC). Screening of molecular differences between AFP-negative and AFP-positive HCC can be helpful for its diagnosis. Methods: Genomic mutations, gene expressions and… read more here.
Keywords: hepatocellular carcinoma; afp; molecular differences; differences afp ... See more keywords
Metabolomic biomarkers for the diagnosis and post-transplant outcomes of AFP negative hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1072775
Abstract: Background Early diagnosis for α-fetoprotein (AFP) negative hepatocellular carcinoma (HCC) remains a critical problem. Metabolomics is prevalently involved in the identification of novel biomarkers. This study aims to identify new and effective markers for AFP… read more here.
Keywords: hepatocellular carcinoma; negative hcc; negative hepatocellular; hcc ... See more keywords
Establishment and validation of nomogram model for the diagnosis of AFP-negative hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1131892
Abstract: Introduction As one of the most common malignant tumors in clinical practice, hepatocellular carcinoma (HCC) is a major threat to human health, where alpha-fetoprotein (AFP) is widely used for early screening and diagnoses. However, the… read more here.
Keywords: hepatocellular carcinoma; nomogram model; hcc; afp negative ... See more keywords
Diagnostic Value of CEUS LI-RADS Version 2017 in Differentiating AFP-Negative Hepatocellular Carcinoma from Other Primary Malignancies of the Liver
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DOI: 10.3390/diagnostics11122250
Abstract: Purpose: To explore the diagnostic value of Contrast-enhanced Ultrasound Liver Imaging Reporting and Data System version 2017 (CEUS LI-RADS v2017) in differentiating alpha-fetoprotein (AFP)-negative hepatocellular carcinoma (HCC) from other primary malignancies (OM) of the liver.… read more here.
Keywords: hcc; afp negative; value; ceus ... See more keywords
Prognostic Value of Des-Gamma-Carboxy Prothrombin in AFP-Negative Hepatocellular Carcinoma Patients Following Liver Resection: A Multicenter Study
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DOI: 10.7150/jca.112394
Abstract: Background: Hepatocellular carcinoma (HCC) is a major global health concern with high postoperative recurrence rates. Des-gamma-carboxy prothrombin (DCP) is a promising biomarker for HCC prognosis, but its optimal cutoff value remains unclear, especially in AFP-negative… read more here.
Keywords: dcp; value; dcp levels; liver resection ... See more keywords
A cost-effective predictive tool for AFP-negative focal hepatic lesions of retrospective study: enhancing clinical triage and decision-making
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DOI: 10.7717/peerj.19150
Abstract: Background Identifying alpha-fetal protein (AFP)-negative focal hepatic lesions presents a significant challenge, particularly in China. We sought to develop an economically portable tool for the diagnosis of benign and malignant liver lesions with AFP-negative status,… read more here.
Keywords: tool; hepatic lesions; predictive tool; afp negative ... See more keywords