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Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24823
Abstract: The accuracy of alpha‐fetoprotein (AFP) as a diagnostic marker for hepatocellular carcinoma (HCC) is insufficient, and the application of abnormal prothrombin (PIVKA‐II) in HCC is still controversial.
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Keywords:
afp pivka;
hepatocellular carcinoma;
serum afp;
value serum ... See more keywords
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Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac027
Abstract: OBJECTIVES To evaluate the prognostic values of serum PIVKA-II (prothrombin induced by vitamin K absence-II) and α-fetoprotein (AFP) and the combination of these analytes for identifying hepatocellular carcinoma (HCC), and to analyze the correlation between…
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Keywords:
afp pivka;
hepatocellular carcinoma;
combination;
clinicopathological features ... See more keywords
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Published in 2025 at "BMC Cancer"
DOI: 10.1186/s12885-025-15040-9
Abstract: Few biomarkers can predict the effectiveness of transcatheter arterial chemoembolization (TACE) in combination with systemic therapies for patients with advanced hepatocellular carcinoma (HCC). This study aimed to evaluate the prognostic significance of changes in alpha-fetoprotein…
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Keywords:
tace;
advanced hepatocellular;
afp pivka;
status ... See more keywords
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Published in 2020 at "Infectious Agents and Cancer"
DOI: 10.1186/s13027-020-00337-0
Abstract: Background To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascular invasion, tumor differentiation and…
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Keywords:
vascular invasion;
pivka;
hbv related;
afp pivka ... See more keywords
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Published in 2025 at "Transplant International"
DOI: 10.3389/ti.2025.14748
Abstract: Despite the development of numerous prognostic models for hepatocellular carcinoma (HCC) recurrence and mortality after liver transplantation, tumor biomarkers such as alpha-fetoprotein (AFP) and protein induced by vitamin K absence-II (PIVKA-II) remain widely used in…
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Keywords:
afp pivka;
hcc;
liver transplantation;
pivka ... See more keywords
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Published in 2025 at "Cancers"
DOI: 10.3390/cancers17183058
Abstract: Simple Summary Patients with unresectable hepatocellular carcinoma (HCC) often receive immune checkpoint inhibitors, but early identification of responders remains challenging. The established CRAFITY score combines C-reactive protein and alpha-fetoprotein (AFP) at baseline, yet its prognostic…
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Keywords:
immunotherapy;
hepatocellular carcinoma;
afp pivka;
crafity afp ... See more keywords
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Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13081442
Abstract: Background: The aim of the present study was to develop an improved diagnostic and prognostic model for HBV-associated HCC by combining AFP with PIVKA-II and other potential serum/plasma protein biomarkers. Methods: A total of 578…
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Keywords:
afp pivka;
index;
hbv;
serum ... See more keywords