Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients
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DOI: 10.1007/s40262-021-01036-8
Abstract: Intramuscular paromomycin monotherapy to treat visceral leishmaniasis (VL) has been shown to be effective for Indian patients, while a similar regimen resulted in lower efficacy in Eastern Africa, which could be related to differences in… read more here.
Keywords: indian patients; eastern african; african indian; visceral leishmaniasis ... See more keywords
MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis
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DOI: 10.1186/s12881-018-0565-1
Abstract: BackgroundPsoriasis and psoriatic arthritis (PsA) are inflammatory associated autoimmune disorders. MicroRNA (miR)-146a plays a crucial role in regulating inflammation. A single nucleotide polymorphism in the miR-146a gene (rs2910164), aberrantly alters its gene expression and linked… read more here.
Keywords: psa; mir 146a; african indian; indian caucasian ... See more keywords