Monoterpene indole alkaloids as leads for targeting multidrug resistant cancer cells from the African medicinal plant Tabernaemontana elegans
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry Reviews"
DOI: 10.1007/s11101-019-09615-1
Abstract: Multidrug resistance (MDR) is the main challenge in cancer treatment. Several mechanisms of MDR have been proposed, such as an increased drug efflux due to the overexpression of ABC drug transporter proteins, or a deregulation… read more here.
Keywords: tabernaemontana elegans; monoterpene indole; indole alkaloids; african medicinal ... See more keywords
A review of the traditional use of southern African medicinal plants for the treatment of fungal skin infections.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112539
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Human dermatophyte infections are one of the most common classes of infection globally, with an estimated 1.7 billion people contracting at least one infection annually. Southern African ethnic groups used multiple plants to… read more here.
Keywords: southern african; plant species; medicinal plants; african medicinal ... See more keywords
Evaluation of the wound healing properties of South African medicinal plants using zebrafish and in vitro bioassays.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114867
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE In South Africa, medicinal plants have a history of traditional use, with many species used for treating wounds. The scientific basis of such uses remains largely unexplored. AIM OF THE STUDY To screen… read more here.
Keywords: wound healing; plant; south african; medicinal plants ... See more keywords
Anti-inflammatory potential of South African medicinal plants used for the treatment of sexually transmitted infections
Sign Up to like & getrecommendations! Published in 2019 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2019.06.023
Abstract: Abstract Inflammation associated with sexually transmitted infection (STIs) often results from delayed diagnosis or treatment, and may result in life-threatening complications. The root or stem bark of plants selected in this study are used by… read more here.
Keywords: sexually transmitted; spectroscopy; treatment; south african ... See more keywords
Identification of potential SARS-CoV-2 inhibitors from South African medicinal plant extracts using molecular modelling approaches
Sign Up to like & getrecommendations! Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2020.07.035
Abstract: Abstract The coronavirus is a group of viruses found in animals as well as humans and have been detected since the 1960s. However, a newly identified form, SARS-CoV-2, has triggered a recent pandemic of respiratory… read more here.
Keywords: using molecular; south african; bioactive compounds; african medicinal ... See more keywords
Bioprospecting of South African Plants as a Unique Resource for Bioactive Endophytic Microbes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00456
Abstract: South Africa has a long history and strong belief in traditional herbal medicines. Using ethnobotanical knowledge as a lead, a large number of South African medicinal plants have been discovered to possess a wide spectrum… read more here.
Keywords: natural products; south african; ethnobotanical knowledge; medicinal plants ... See more keywords
The use of African medicinal plants in cancer management
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1122388
Abstract: Cancer is the third leading cause of premature death in sub-Saharan Africa. Cervical cancer has the highest number of incidences in sub-Saharan Africa due to high HIV prevalence (70% of global cases) in African countries… read more here.
Keywords: cancer management; anticancer; medicinal plants; african medicinal ... See more keywords