Novel lead compounds in pre-clinical development against African sleeping sickness.
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DOI: 10.1039/c7md00280g
Abstract: Human African trypanosomiasis (HAT), also known as African sleeping sickness, is caused by parasitic protozoa of the genus Trypanosoma. As the disease progresses, the parasites cross the blood brain barrier and are lethal for the… read more here.
Keywords: novel lead; development; african sleeping; sleeping sickness ... See more keywords
Resolving the apparent transmission paradox of African sleeping sickness
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DOI: 10.1371/journal.pbio.3000105
Abstract: Human African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease found throughout sub-Saharan Africa. The disease is close to elimination in many areas, although it was similarly close to elimination once before and… read more here.
Keywords: transmission paradox; transmission; african sleeping; apparent transmission ... See more keywords
Basic Biology of Trypanosoma brucei with reference to the development of chemotherapies.
Sign Up to like & getrecommendations! Published in 2021 at "Current pharmaceutical design"
DOI: 10.2174/1381612827666210119105008
Abstract: Trypanosoma brucei are protozoan parasites that causes the lethal human disease African sleeping sickness, and the economically devastating disease of cattle, Nagana. African sleeping sickness, or Human African Trypanosomiasis (HAT) threatens 65 million people, and… read more here.
Keywords: african sleeping; biology; disease; trypanosoma brucei ... See more keywords