Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.23285
Abstract: This cohort study investigates the association of epigenetic age acceleration with odds of surviving to age 90 with intact function among older US women. read more here.
Keywords: among older; epigenetic age; older women; age ... See more keywords
Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.19771
Abstract: This cross-sectional study analyzes whether associations of epigenetic age acceleration (EAA) with cancer treatment vary by race and ethnicity among survivors of childhood cancer and whether socioeconomic factors mediate the associations. read more here.
Keywords: cancer; age acceleration; epigenetic age; race ethnicity ... See more keywords
Causal Associations of Epigenetic Age Acceleration With Stroke and Its Functional Outcome: A Two‐Sample, Two‐Step Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70412
Abstract: Emerging evidence from observational studies suggested that epigenetic age acceleration may result in an increased incidence of stroke and poorer functional outcomes after a stroke. However, the causality of these associations remains controversial and may… read more here.
Keywords: stroke functional; age; age acceleration; epigenetic age ... See more keywords
Association between depression and epigenetic age acceleration: A co‐twin control study
Sign Up to like & getrecommendations! Published in 2022 at "Depression and Anxiety"
DOI: 10.1002/da.23279
Abstract: Prior studies have shown inconsistent findings of an association between depression and epigenetic aging. DNA methylation (DNAm) age acceleration can measure biological aging. We adopted a robust co‐twin control study design to examine whether depression… read more here.
Keywords: association depression; depression; depression epigenetic; age acceleration ... See more keywords
Grip strength is inversely associated with DNA methylation age acceleration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13110
Abstract: There is a large body of evidence linking muscular weakness, as determined by low grip strength, to a host of negative ageing‐related health outcomes. Given these links, grip strength has been labelled a ‘biomarker of… read more here.
Keywords: strength; dna methylation; age acceleration; grip strength ... See more keywords
Associations between lifestyle factors, physiological conditions, and epigenetic age acceleration in an Asian population
Sign Up to like & getrecommendations! Published in 2025 at "Biogerontology"
DOI: 10.1007/s10522-025-10195-1
Abstract: Epigenetic clocks use DNA methylation (DNAm) levels to predict an individual’s biological age. However, relationships between lifestyle/biomarkers and epigenetic age acceleration (EAA) in Asian populations remain unknown. We here explored associations between lifestyle factors, physiological… read more here.
Keywords: age; factors physiological; age acceleration; epigenetic age ... See more keywords
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume.
Sign Up to like & getrecommendations! Published in 2022 at "GeroScience"
DOI: 10.1007/s11357-022-00558-8
Abstract: The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer's Disease (AD). Whilst studies have reported associations with AD… read more here.
Keywords: hippocampal volume; age acceleration; age; epigenetic clocks ... See more keywords
Maternal Prenatal Anxiety and the Fetal Origins of Epigenetic Aging
Sign Up to like & getrecommendations! Published in 2021 at "Biological psychiatry"
DOI: 10.1016/j.biopsych.2021.07.025
Abstract: BACKGROUND The fetal origins of mental health is a well-established framework that currently lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal-Epigenetic (PedBE) clock is a novel epigenetic tool that associates… read more here.
Keywords: fetal origins; anxiety; age; origins epigenetic ... See more keywords
DNA methylation age acceleration is associated with age of onset in Chinese spinocerebellar ataxia type 3 patients
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2022.02.002
Abstract: Spinocerebellar ataxia type 3 (SCA3), also known as Machado Joseph disease (MJD), is a common dominantly inherited ataxia, and has heterogeneous clinical features and variable age of onset, ranging from 10 to 78 years. Repeats… read more here.
Keywords: age; dnam age; age onset; acceleration associated ... See more keywords
Biological aging in schizophrenia and psychosis severity: DNA methylation analysis
Sign Up to like & getrecommendations! Published in 2021 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2020.113646
Abstract: The physiological changes associated with normal aging are known to occur earlier in individuals with schizophrenia (SCZ). One of the phenomena linked with normal aging is the change in patterns of epigenetic modifications. We recruited… read more here.
Keywords: dna methylation; age; age acceleration; psychosis severity ... See more keywords
Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks
Sign Up to like & getrecommendations! Published in 2022 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2021.105643
Abstract: OBJECTIVE This retrospective cross-sectional study was designed to explore whether the experience of childhood adversity was associated with epigenetic age acceleration in mid-life and older ages using the next generation GrimAge and Pace of Aging… read more here.
Keywords: age; adversity; age acceleration; life ... See more keywords