Annual stability of the plasma Aß40/42 ratio and associated factors.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51770
Abstract: OBJECTIVE The plasma Aß40/42 ratio is a biomarker of brain amyloidosis. However, the threshold difference between amyloid positivity and negativity is only 10-20% and fluctuates with circadian rhythms, aging, and APOE-ε4 during the decades of… read more here.
Keywords: age dependent; annual stability; age; stability plasma ... See more keywords
Age-dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury.
Sign Up to like & getrecommendations! Published in 2022 at "Human brain mapping"
DOI: 10.1002/hbm.25811
Abstract: Mild Traumatic brain injury (mTBI) is a signature wound in military personnel, and repetitive mTBI has been linked to age-related neurogenerative disorders that affect white matter (WM) in the brain. However, findings of injury to… read more here.
Keywords: brain injury; injury; traumatic brain; age dependent ... See more keywords
Reduced cardiomyocyte Na+ current in the age‐dependent murine Pgc‐1β −/− model of ventricular arrhythmia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27183
Abstract: Abstract Peroxisome proliferator‐activated receptor‐γ coactivator‐1 deficient (Pgc‐1β −/−) murine hearts model the increased, age‐dependent, ventricular arrhythmic risks attributed to clinical conditions associated with mitochondrial energetic dysfunction. These were accompanied by compromised action potential (AP) upstroke… read more here.
Keywords: voltage; age dependent; murine; age ... See more keywords
Confirmation of neurometabolic diagnoses using age‐dependent cerebrospinal fluid metabolomic profiles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12253
Abstract: Timely diagnosis is essential for patients with neurometabolic disorders to enable targeted treatment. Next‐Generation Metabolic Screening (NGMS) allows for simultaneous screening of multiple diseases and yields a holistic view of disturbed metabolic pathways. We applied… read more here.
Keywords: age dependent; age; csf; neurometabolic disorders ... See more keywords
Age‐Dependent Changes in Knee Cartilage T1, T2, and T1p Simultaneously Measured Using MRI Fingerprinting
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28451
Abstract: Magnetic resonance fingerprinting (MRF) techniques have been recently described for simultaneous multiparameter cartilage mapping of the knee although investigation of their ability to detect early cartilage degeneration remains limited. read more here.
Keywords: age dependent; cartilage; cartilage t1p; dependent changes ... See more keywords
Dynamical properties in an SVEIR epidemic model with age‐dependent vaccination, latency, infection, and relapse
Sign Up to like & getrecommendations! Published in 2021 at "Mathematical Methods in the Applied Sciences"
DOI: 10.1002/mma.7583
Abstract: An SVEIR epidemic model with continuous age‐dependent vaccination, latency, infection, and disease relapse is proposed and analyzed in this paper. The dynamical behaviors including the derivation of basic reproduction number R0 , the existence and… read more here.
Keywords: dependent vaccination; sveir epidemic; vaccination latency; model ... See more keywords
Age-dependent dose calculations for common PET radionuclides and brain radiotracers in non-human primate computational models.
Sign Up to like & getrecommendations! Published in 2020 at "Medical physics"
DOI: 10.1002/mp.14333
Abstract: PURPOSE The combination of nonhuman primates (NHPs) with state-of-the-art molecular imaging technologies allows for within-subject longitudinal research aiming at gaining new insights into human normal and disease conditions and provides an ideal foundation for future… read more here.
Keywords: age dependent; absorbed doses; model; molecular imaging ... See more keywords
Age-dependent differences in response to partial-thickness cartilage defects in a rat model as a measure to evaluate the efficacy of interventions for cartilage repair
Sign Up to like & getrecommendations! Published in 2018 at "Cell and Tissue Research"
DOI: 10.1007/s00441-018-2914-y
Abstract: The objectives of this study are (1) to examine age-dependent longitudinal differences in histological responses after creation of partial-thickness articular cartilage defects (PTCDs) in rats and to use this model (2) to objectively evaluate the… read more here.
Keywords: cartilage repair; week; age dependent; partial thickness ... See more keywords
Natural radioactivity measurements and age-dependent dose assessment in groundwater from Al-Zulfi, Al-Qassim and Al-Majmaah regions, Saudi Arabia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-018-6053-4
Abstract: In this study, the levels of natural radioactivity in the groundwater samples collected from 26 different locations in Al-Zulfi, Al-Qassim and Al-Majmaah regions were determined. The estimated average values of 226Ra, 228Ra, 40K, gross α… read more here.
Keywords: natural radioactivity; qassim majmaah; age dependent; zulfi qassim ... See more keywords
Age-Dependent Neurochemical Remodeling of Hypothalamic Astrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0786-x
Abstract: The hypothalamus is a crucial integrative center in the central nervous system, responsible for the regulation of homeostatic activities, including systemic energy balance. Increasing evidence has highlighted a critical role of astrocytes in orchestrating hypothalamic… read more here.
Keywords: age dependent; hypothalamic astrocytes; age; remodeling hypothalamic ... See more keywords
Direct evidence for the age-dependent demise of GNAS-mutated cells in oral fibrous dysplasia.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.05.018
Abstract: OBJECTIVE Fibrous dysplasia (FD) is a benign bone disease characterized by fibro-osseous lesions. FD is caused by somatic mutations in the gene, guanine nucleotide-binding protein, alpha stimulating activity polypeptide 1 (GNAS), which encodes the G… read more here.
Keywords: age dependent; evidence age; mutated cells; fibrous dysplasia ... See more keywords