TARGETING SIRT1 RESCUES AGE- AND OBESITY-INDUCED HUMAN MICROVASCULAR DYSFUNCTION
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DOI: 10.1097/01.hjh.0000835692.74272.a2
Abstract: Objective: Experimental evidence suggests a relevant role of SIRT1 in age- and metabolic-related vascular dysfunction. Whether these effects hold true in the human microvasculature is unknown. We aimed to investigate the role of SIRT1 in… read more here.
Keywords: age obesity; sirt1; microvascular dysfunction; age ... See more keywords
The effects of age and obesity on postprandial dynamics of serum testosterone levels in men
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DOI: 10.1111/cen.14141
Abstract: Guidelines recommend using fasting samples to evaluate testosterone (T) levels in men, as free and total T levels decrease postprandially. However, it is not clear whether these dynamics are affected by age or obesity. This… read more here.
Keywords: levels men; age obesity; testosterone levels;
Translating MSC Therapy in the Age of Obesity
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DOI: 10.3389/fimmu.2022.943333
Abstract: Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option to treat a number of inflammatory conditions including COVID-19 acute respiratory distress syndrome (ARDS). As rates of obesity and metabolic disease continue… read more here.
Keywords: msc therapy; age obesity; therapy; translating msc ... See more keywords