Association of Lipid, Inflammatory, and Metabolic Biomarkers With Age at Onset for Incident Coronary Heart Disease in Women.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.7073
Abstract: Importance Risk profiles for premature coronary heart disease (CHD) are unclear. Objective To examine baseline risk profiles for incident CHD in women by age at onset. Design, Setting, and Participants A prospective cohort of US… read more here.
Keywords: chd onset; risk; age; disease ... See more keywords
Study Selection Bias and Racial or Ethnic Disparities in Estimated Age at Onset of Cardiometabolic Disease Among Midlife Women in the US
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.40665
Abstract: This cohort study evaluates the association of selection bias into and out of cohort studies with racial or ethnic disparities in the estimation of age at onset of cardiometabolic disease in a cohort of midlife… read more here.
Keywords: onset cardiometabolic; selection bias; ethnic disparities; racial ethnic ... See more keywords
Investigation of the COMT Val158Met variant association with age of onset of psychosis, adjusting for cannabis use
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.850
Abstract: COMT rs4680 (Val158Met) genotype moderates the effect of cannabis on the age of onset of psychosis (AoP). We investigated the association between rs4680 and AoP, after adjusting for relevant covariates, in a Canadian Caucasian sample. read more here.
Keywords: cannabis; onset psychosis; comt; age onset ... See more keywords
Hoarding: A meta‐analysis of age of onset
Sign Up to like & getrecommendations! Published in 2019 at "Depression and Anxiety"
DOI: 10.1002/da.22896
Abstract: Hoarding disorder is present in 2–6% of the population and can have an immense impact on the lives of patients and their families. Before its inclusion the Diagnostic and Statistical Manual of Mental Disorders, 5th… read more here.
Keywords: age; age onset; onset hoarding; meta analysis ... See more keywords
Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3627
Abstract: Bones’ shapes and structures adapt to the muscle and reaction forces they experience during everyday movements. Onset of independent walking, at approximately 12 months, represents the first postnatal exposure of the lower limbs to the… read more here.
Keywords: shape; hip shape; age; walking age ... See more keywords
LARGE‐PD: Examining the genetics of Parkinson's disease in Latin America
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.27081
Abstract: Expanded alleles accounted for 74.3% of the observed variability in the age at onset, whereas normal alleles explained a discrete additional 0.5% of the total age at onset variance, and 1.95% of the variance of… read more here.
Keywords: expanded alleles; wildtype; ataxin; genetics ... See more keywords
Age at Onset of LRRK2 p.Gly2019Ser Is Related to Environmental and Lifestyle Factors
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28238
Abstract: The effect of environmental and lifestyle factors on patients with LRRK2 (leucine‐rich repeat kinase 2) p.Gly2019Ser (LRRK2+/PD+) compared to idiopathic PD (iPD) has yet to be thoroughly investigated. read more here.
Keywords: onset lrrk2; gly2019ser related; environmental lifestyle; lrrk2 gly2019ser ... See more keywords
Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29157
Abstract: Aging is the strongest risk factor for Parkinson's disease (PD), which is a clinically heterogeneous movement disorder with highly variable age at onset. DNA methylation age (DNAm age) is an epigenetic clock that could reflect… read more here.
Keywords: age onset; parkinson disease; epigenetic clock; age ... See more keywords
Age at onset of alcohol consumption and its association with alcohol misuse in adulthood
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12302
Abstract: This study aimed to explore the association between early age onset of alcohol consumption and alcohol misuse in adulthood. read more here.
Keywords: alcohol consumption; alcohol misuse; misuse adulthood; age onset ... See more keywords
Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-022-11041-x
Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disorder. Genetic modifiers, environmental factors and gene–environment interactions have been found to modify PD risk and disease progression. The objective of this study was to evaluate the association… read more here.
Keywords: coffee; disease; parkinson disease; age onset ... See more keywords
Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neurology"
DOI: 10.1007/s00415-024-12452-8
Abstract: Aquaporin-4 (AQP4) antibody-associated neuromyelitis optica spectrum disorder (NMOSD) is an antibody-mediated inflammatory disease of the central nervous system. We have undertaken a systematic review and meta-analysis to ascertain the sex ratio and mean age of… read more here.
Keywords: antibody; age onset; sex ratio; aqp4 antibody ... See more keywords