Trends in Testosterone Prescribing for Age-related Hypogonadism in Men With and Without Heart Disease
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2018.6505
Abstract: This cohort study examines the trend in prescription testosterone use among male Medicare beneficiaries with and without coronary artery disease aged 50 years or older. read more here.
Keywords: testosterone prescribing; prescribing age; trends testosterone; age related ... See more keywords
Assessment of Frailty Index at 66 Years of Age and Association With Age-Related Diseases, Disability, and Death Over 10 Years in Korea
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.48995
Abstract: Key Points Question Is a frailty index measure at 66 years of age associated with incident age-related chronic disease, disability, and death? Findings This nationwide cohort study of 968 885 Korean individuals found that a frailty… read more here.
Keywords: frailty index; age related; years age; age ... See more keywords
Association of C-Reactive Protein Genetic Polymorphisms With Late Age-Related Macular Degeneration
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.2191
Abstract: Importance C-reactive protein (CRP) is a circulating inflammatory marker associated with late age-related macular degeneration (AMD). It remains uncertain whether the association between CRP concentrations and AMD is causal. Objective To assess whether CRP (OMIM… read more here.
Keywords: crp; age related; age; association ... See more keywords
Association Between the Cilioretinal Artery and Choroidal Neovascularization in Age-Related Macular Degeneration: A Secondary Analysis From the Age-Related Eye Disease Study
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2018.2650
Abstract: Importance A hemodynamic role in the pathogenesis of age-related macular degeneration (AMD) has been proposed, but to our knowledge, an association between retinal vasculature and late AMD has not been investigated. Objective To determine whether… read more here.
Keywords: age related; association cilioretinal; artery; cilioretinal artery ... See more keywords
Association of Dietary and Supplementary Calcium Intake With Age-Related Macular Degeneration: Age-Related Eye Disease Study Report 39
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2019.0292
Abstract: Importance Previous studies of the role of dietary and supplementary calcium in age-related macular degeneration (AMD) have produced mixed results, suggesting that supplementation and decreased dietary intake are both harmful. Objective To evaluate the association… read more here.
Keywords: intake; age related; supplementary calcium; calcium intake ... See more keywords
Association of Dietary Nitrate and a Mediterranean Diet With Age-Related Macular Degeneration Among US Adults: The Age-Related Eye Disease Study (AREDS) and AREDS2.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.5404
Abstract: Importance Low dietary nitrate intake has previously been suggested to be a risk factor for age-related macular degeneration (AMD) progression; however, this finding has not been replicated in other cohorts or adjusted for dietary patterns.… read more here.
Keywords: age related; nitrate intake; dietary nitrate; intake ... See more keywords
Association of Metformin With the Development of Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.5567
Abstract: Importance Age-related macular degeneration (AMD) is a leading cause of blindness with no treatment available for early stages. Retrospective studies have shown an association between metformin and reduced risk of AMD. Objective To investigate the… read more here.
Keywords: arm; age related; association metformin; age ... See more keywords
Elevated YKL-40 serum levels may contribute to wet age-related macular degeneration via the ERK1/2 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13223
Abstract: Choroidal neovascularization (CNV) is a key characteristic of wet age-related macular degeneration (AMD) that can lead to severe vision loss in the elderly. Anti-VEGF therapy is currently the premier strategy for wet AMD, but it… read more here.
Keywords: age related; erk1 pathway; wet age; wet amd ... See more keywords
Common age‐related neuropathologies and yearly variability in cognition
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50857
Abstract: Cognitive variability is a potentially important source of heterogeneity in longitudinal cognitive profiles. We examined the extent to which common age‐related neuropathologies including Lewy bodies and Alzheimer’s disease (AD) contribute to yearly variability in late… read more here.
Keywords: age related; common age; yearly variability; variability ... See more keywords
Clinicoradiologic data of familial cerebral cavernous malformation with age‐related disease burden
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DOI: 10.1002/acn3.51728
Abstract: Familial cerebral cavernous malformation (FCCM) is an autosomal dominant disease induced by loss‐of‐function mutations in three CCM genes, KRIT1, CCM2, and PDCD10. However, previous studies paid little attention to analyzing the radiologic features and age‐related… read more here.
Keywords: familial cerebral; age related; disease; related disease ... See more keywords
Age‐related phenotype and biomarker changes in SSADH deficiency
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DOI: 10.1002/acn3.696
Abstract: Succinic Semialdehyde Dehydrogenase (SSADH) deficiency is a disorder of elevated gamma‐amino butyric acid (GABA) and gamma hydroxybutyric acid (GHB) and a complex neuropsychiatric profile. Adult reports suggest worsening epilepsy and high SUDEP risk. read more here.
Keywords: phenotype biomarker; biomarker changes; ssadh deficiency; age related ... See more keywords