Reduced mitophagy in the cochlea of aged C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.110946
Abstract: An increase in mitochondrial damage has been associated with a decline in the ability to mitigate damage through mitophagy in age-related pathologies. The present study aimed to investigate the changes of mitophagy in a mouse… read more here.
Keywords: cochlea mice; mice aged; cochlea; mice ... See more keywords
Growth hormone improved oxidative stress in follicle fluid by influencing Nrf2/Keap1 expression in women of advanced age undergoing IVF
Sign Up to like & getrecommendations! Published in 2022 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2021.2003325
Abstract: Abstract Objectives To investigate whether growth hormone (GH) can improve oxidative stress (OS) by affecting) /nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) in women of advanced age undergoing in vitro fertilization… read more here.
Keywords: aged group; women advanced; group; advanced age ... See more keywords
The short-term and oncologic outcomes of younger VS older colorectal cancer patients undergoing primary surgery: a propensity score matching analysis
Sign Up to like & getrecommendations! Published in 2022 at "BMC Cancer"
DOI: 10.1186/s12885-022-09246-4
Abstract: Purpose The purpose of the current study is to analyze the difference of short-term and oncologic outcomes between younger and older colorectal cancer (CRC) patients who underwent primary CRC surgery using a propensity score matching… read more here.
Keywords: aged group; group; term oncologic; surgery ... See more keywords
Next-generation Sequencing Reveals Age-dependent Genetic Underpinnings in Lung adenocarcinoma
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DOI: 10.7150/jca.65370
Abstract: Background: More than 40% of lung cancer patients are diagnosed at ages over 70. However, the genomic and clinical characteristics among them remain elusive. Here, we performed targeted capture sequence to characterize the mutational spectrum… read more here.
Keywords: luad patients; lung adenocarcinoma; age; group ... See more keywords