Teaching old mice new tricks: the utility of aged mouse models of C. difficile infection to study pathogenesis and rejuvenate immune response
Sign Up to like & getrecommendations! Published in 2021 at "Gut Microbes"
DOI: 10.1080/19490976.2021.1966255
Abstract: ABSTRACT Background Clostridioides difficile is a serious problem for the aging population. Aged mouse model of C. difficile infection (CDI) has emerged as a valuable tool to evaluate the mechanism of aging in CDI. Methods… read more here.
Keywords: aged mouse; mouse models; difficile infection; infection ... See more keywords
The N6‐methyladenosine RNA landscape in the aged mouse hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13755
Abstract: The aged brain is associated with an inevitable decline in cognitive function and increased vulnerability to neurodegenerative disorders. Multiple molecular hallmarks have been associated with the aging nervous system through transcriptomics and proteomic studies. Recently,… read more here.
Keywords: rna; mouse hippocampus; aged mouse; hippocampus ... See more keywords