Effects of exercise training on neuromuscular junctions and their active zones in young and aged muscles
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DOI: 10.1016/j.neurobiolaging.2020.07.001
Abstract: The neuromuscular junction (NMJ) connects the motor neuron with myofibers allowing muscle contraction. Both aging and increased activity result in NMJ remodeling. Here, the effects of exercise were examined in young and aged soleus muscles.… read more here.
Keywords: active zones; aged muscles; training neuromuscular; young aged ... See more keywords
STAT3 inhibition recovers regeneration of aged muscles by restoring autophagy in muscle stem cells
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DOI: 10.26508/lsa.202302503
Abstract: This study shows that STAT3 regulates MuSC function by both transcription-dependent and transcription-independent control of autophagy. STAT3 inhibition reverses age-dependent impairment of muscle regeneration, by restoring autophagy in aged MuSCs. Age-related reduction in muscle stem… read more here.
Keywords: restoring autophagy; muscle; inhibition; aged muscles ... See more keywords