A Visible‐ and NIR‐Light Responsive Photothermal Therapy Agent by Chirality‐Dependent MoO3−x Nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201906311
Abstract: Chirality‐based semiconducting nanocrystals, as an emerging area, are envisioned to have great potential in chiral sensing, biomedicine, and chiroptical devices. Herein, chiral substoichiometric molybdenum oxide (l/d‐Cys‐MoO3−x) nanoparticles are synthesized via step‐by‐step reduction treatment with chiral… read more here.
Keywords: agent; moo3 nanoparticles; photothermal therapy; chirality ... See more keywords
A Concerted Redox‐ and Light‐Activated Agent for Controlled Multimodal Therapy against Hypoxic Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210363
Abstract: Hypoxia represents a remarkably exploitable target for cancer therapy, is encountered only in solid human tumors, and is highly associated with cancer resistance and recurrence. Here, a hypoxia‐activated mitochondria‐accumulated Ru(II) polypyridyl prodrug functionalized with conjugated… read more here.
Keywords: cancer; controlled multimodal; agent; hypoxic ... See more keywords
Time for the Next Step in Clinical Trial Evolution?
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26655
Abstract: In this issue of Annals of Neurology, Pittock and colleagues report the primary outcome of a phase 3 clinical trial of ravulizumab for aquaporin-4-positive neuromyelitis optica spectrum disorder (NMOSD). Ravulizumab is a second-in-class terminal complement… read more here.
Keywords: medication; neurology; agent; trial ... See more keywords
Soy protein isolate nanocomposite film enriched with eugenol, an antimicrobial agent: Interactions and properties
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45941
Abstract: Nanocomposites films were designed from soy protein isolates (SPI), clays (Na+-MMT), and eugenol an antimicrobial agent. Interactions between Na+-MMT and eugenol were evidenced by a shift of the d-spacing by X-ray diffraction analysis. The addition… read more here.
Keywords: agent; antimicrobial agent; eugenol antimicrobial; soy protein ... See more keywords
Fully distributed coordination learning control of second‐order nonlinear multi‐agent systems with input saturation
Sign Up to like & getrecommendations! Published in 2020 at "Asian Journal of Control"
DOI: 10.1002/asjc.2330
Abstract: This paper develops the coordination learning control of second‐order non‐linear multi‐agent systems with input saturation. Fully distributed learning consensus protocols with fully saturated parameter adaptive updating laws are designed. Although there exists input saturation in… read more here.
Keywords: control second; agent; learning control; coordination learning ... See more keywords
The Photosensitising Clinical Agent Verteporfin Is an Inhibitor of SPAK and OSR1 Kinases
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800272
Abstract: STE20/SPS1‐related proline/alanine‐rich kinase (SPAK) and oxidative‐stress‐responsive kinase 1 (OSR1) are two serine/threonine protein kinases that play key roles in regulating ion homeostasis. Various SPAK and OSR1 mouse models exhibited reduced blood pressure. Herein, the discovery of… read more here.
Keywords: agent; spak; verteporfin; osr1 kinases ... See more keywords
Chemosensitivity‐Gene Expression Correlations and Functional Enrichment Analysis Provide Insight into the Mechanism of Action of a Platinum‐Acridine Anticancer Agent
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200331
Abstract: NCI‐60 growth inhibition and gene expression profiles were analyzed using Pearson correlation and functional enrichment computational tools to demonstrate critical mechanistic differences between a nucleolus‐targeting platinum‐acridine anticancer agent (PA) and other DNA‐directed chemotherapies. The results… read more here.
Keywords: functional enrichment; agent; platinum acridine; gene expression ... See more keywords
Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of 68Ga Labeling and Complex Stability Characteristics with Established Chelators
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200495
Abstract: [68Ga]Ga3+ can be introduced into receptor‐specific peptidic carriers via different chelators to obtain radiotracers for Positron Emission Tomography imaging and the chosen chelating agent considerably influences the in vivo pharmacokinetics of the corresponding radiopeptides. A chelator… read more here.
Keywords: cross bridged; bridged chelating; bifunctional cross; established chelators ... See more keywords
Development and characterization of pectin and chitosan films incorporated with a new cross-linking agent.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12395
Abstract: BACKGROUND In this study, a new crosslinking agent (CA) containing whey protein, papin, glycerin, and epigallocatechin gallate (EGCG), was prepared. The effects of CA content (0, 10, 20, 30, and 40%, v/v) on food packaging… read more here.
Keywords: pectin chitosan; food; cross linking; agent ... See more keywords
EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201700203
Abstract: For successful nonviral gene delivery, cationic polymers are promising DNA carrier, which need to comprise several functionalities. The current work focuses on the postincorporation of epidermal growth factor receptor (EGFR) targeted PEGylation agents onto lipopolyplexes… read more here.
Keywords: sequence defined; agent; egfr targeting; sequence ... See more keywords
Wealth and the principal–agent matching
Sign Up to like & getrecommendations! Published in 2021 at "Managerial and Decision Economics"
DOI: 10.1002/mde.3402
Abstract: I study the role the agent's wealth plays in the principal-agent matching with moral hazard and limited liability. I consider wealth and talent as the agent's type, and size as the firm's (principal's) type. Because… read more here.
Keywords: agent; wealth; principal agent; wealth principal ... See more keywords