Infigratinib (BGJ398): an investigational agent for the treatment of FGFR-altered intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2021.1864320
Abstract: ABSTRACT Introduction The fibroblast growth factor receptor (FGFR) pathway is essential in cell proliferation, differentiation, migration, and survival. Cancers such as intrahepatic cholangiocarcinoma (IHCA) have demonstrated alterations of FGFR allowing unregulated growth. Infigratinib (BGJ398) is… read more here.
Keywords: agent treatment; fgfr; treatment; intrahepatic cholangiocarcinoma ... See more keywords
Bedaquiline as a potential agent in the treatment of M. intracellulare and M. avium infections
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DOI: 10.1183/13993003.01969-2016
Abstract: Recently in this journal, Salfinger and Migliori [1] discussed the accessibility of bedaquiline drug susceptibility testing and the analysis of minimum inhibitory concentrations (MICs) for strains of Mycobacterium tuberculosis. As the recommended treatments for diseases… read more here.
Keywords: agent treatment; potential agent; bedaquiline potential; avium ... See more keywords
Polysaccharides, Next Potential Agent for the Treatment of Epilepsy?
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DOI: 10.3389/fphar.2022.790136
Abstract: Epilepsy is a chronic neurological disorder. Current pharmacological therapies for epilepsy have limited efficacy that result in refractory epilepsy (RE). Owing to the limitations of conventional therapies, it is needed to develop new anti-epileptic drugs.… read more here.
Keywords: potential agent; epilepsy; agent treatment; treatment epilepsy ... See more keywords
Metformin as a Potential Agent in the Treatment of Multiple Sclerosis
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DOI: 10.3390/ijms21175957
Abstract: Metformin, a synthetic derivative of guanidine, is commonly used as an oral antidiabetic agent and is considered a multi-vector application agent in the treatment of other inflammatory diseases. Recent studies have confirmed the beneficial effect… read more here.
Keywords: agent; agent treatment; multiple sclerosis; metformin ... See more keywords
GR-2397: Review of the Novel Siderophore-like Antifungal Agent for the Treatment of Invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8090909
Abstract: GR-2397 (previously VL-2397, ASP2397) is a first-in-class antifungal agent for the treatment of invasive aspergillosis. This siderophore-like molecule resembles ferrichrome; however, it is differentiated by three amino acid changes and an aluminum rather than iron… read more here.
Keywords: agent treatment; antifungal agent; treatment invasive; treatment ... See more keywords