Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitors
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DOI: 10.1097/cm9.0000000000000685
Abstract: Abstract Epigenetic regulation includes changes of DNA methylation and modifications of histone proteins and is essential for normal physiologic functions, especially for controlling gene expression. Epigenetic dysregulation plays a key role in disease pathogenesis and… read more here.
Keywords: histone deacetylase; deacetylase inhibitors; hypomethylating agents; epigenetic therapies ... See more keywords